Protein Alignment CG32373 and efemp2a

DIOPT Version :10

• Sequence 1: NP_729293.1
• Gene: CG32373 / 318000
• FlyBaseID: FBgn0052373
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_001008587.1
• Gene: efemp2a / 494044
• ZFINID: ZDB-GENE-041212-8
• Length: 440
• Species: Danio rerio
• Alignment Length: 276
• Identity: 74/276 - (26%)
• Similarity: 112/276 - (40%)
• Gaps: 82/276 - (29%)

  Fly   101 GLKP---NCIKIGKGNTHSMKQKKMRCRIDNGGC--AHIC--NRSTHKCECYEGYTLNSTDLRSC 158
            |.:|   :|:.:.:            |..|:..|  :..|  ...:..|:|.:||....|:   |
Zfish   110 GFEPQQDSCVDVDE------------CERDSHDCQPSQQCFNTEGSFSCQCPDGYRKVGTE---C 159

  Fly   159 NDIDECKESNGGCSQVCNNLPGEFICTCNSGFEIDESDEKTCLDIDECADPELSWDCTAGCKNLN 223
            .|||||:...  |...|.|:||.|.|.|..||:: ..:.::|:|:|||.   :...|:..|.|..
Zfish   160 IDIDECRYRY--CQHRCVNVPGSFSCQCEPGFQL-AGNNRSCIDVDECG---MGAPCSQWCYNTY 218

  Fly   224 GTYKCLPSLVGRVEPTDGDGFSPGEIVCKSGFKLSDDGSECQDINECDLADIDSDSWRMTYRYCE 288
            ||:.|.                     |:.|::|..||..|.||:||..:..          .|:
Zfish   219 GTFLCR---------------------CEQGYELGPDGFACNDIDECSYSSY----------LCQ 252

  Fly   289 HKCENTVGSYICHCPQGYHLL-----DDQNSC---------------ILDGSKLPPSKDA--PVS 331
            ::|.|..|.:.|.||:||.||     .|.|.|               |..|.|...:|..  |..
Zfish   253 YQCVNEHGKFSCVCPEGYQLLGTRLCQDINECETGAHQCSDGQTCVNIHGGHKCVDNKSCQDPYM 317

  Fly   332 QEAPRKDICPLFKGPA 347
            |.:..:.:||:.| ||
Zfish   318 QVSENRCMCPVSK-PA 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32373	NP_729293.1	FXa_inhibition	124..158	CDD:464251	9/37 (24%)
		FXa_inhibition	164..200	CDD:464251	11/35 (31%)
		FXa_inhibition	287..315	CDD:464251	13/32 (41%)
		CCP	340..398	CDD:153056	5/8 (63%)
efemp2a	NP_001008587.1	EGF_CA	120..151	CDD:429571	6/42 (14%)
		FXa_inhibition	170..198	CDD:464251	10/28 (36%)
		vWFA	<195..235	CDD:469594	14/63 (22%)
		EGF_CA	240..271	CDD:214542	12/40 (30%)
		EGF_CA	280..307	CDD:429571	6/26 (23%)