Protein Alignment CG32373 and Efemp1

DIOPT Version :9

• Sequence 1: NP_001261534.1
• Gene: CG32373 / 318000
• FlyBaseID: FBgn0052373
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_001012039.1
• Gene: Efemp1 / 305604
• RGDID: 1308528
• Length: 493
• Species: Rattus norvegicus
• Alignment Length: 354
• Identity: 86/354 - (24%)
• Similarity: 129/354 - (36%)
• Gaps: 123/354 - (34%)

  Fly    52 PRIKNAKASVKLRR----------NGEHVFLVTYYSCRVNYKLKRAKDNALY----CSNGIWLGL 102
            |.::..:.:..:||          |..|     ...|...|  ::::.|...    |::|
  Rat   128 PEVQTGRNNFVIRRNPADPQRIPSNPSH-----RIQCAAGY--EQSEHNVCQDIDECTSG----- 180

  Fly   103 KPNCIKIGKGNTHSMKQKKMRCRIDNGGCAHICNRSTHKCECYEGYTLNSTDLRSCNDIDECKES 167
                       ||:       ||:|. .|.::  |.:..|.|..||....   ..|.|||||...
  Rat   181 -----------THN-------CRLDQ-VCINL--RGSFTCHCLPGYQKRG---EQCVDIDECSVP 221

  Fly   168 NGGCSQVCNNLPGEFICTCNSGFEIDESDEKTCLDIDECADPELSWDCTAGCKNLNGTYKCLPSL 232
             ..|.|.|.|.||.|.|.||.||:: .::..||:||:||   :.|..|...|.|:.|::.|
  Rat   222 -PYCHQGCVNTPGSFYCQCNPGFQL-AANNYTCVDINEC---DASNQCAQQCYNILGSFIC---- 277

  Fly   233 VGRVEPTDGDGFSPGEIVCKSGFKLSDDGSECQDINECDLADIDSDSWRMTYRYCEHKCENTVGS 297
                             .|..|::||.|...|:||:||          |.:...|:::|.|..|.
  Rat   278 -----------------QCNQGYELSSDRLNCEDIDEC----------RTSSYLCQYQCVNEPGK 315

  Fly   298 YICHCPQGYHLL-----DDQNSCILDGSKLPPSKDAPVSQEAPRKDICPLFKGPANGKASCDKYL 357
            :.|.|||||.::     .|.|.|             ..:.|....::|..:.|
  Rat   316 FSCMCPQGYQVVRSRTCQDINEC-------------ETTNECREDEMCWNYHG------------ 355

  Fly   358 QNGFNYTRC--NITCNAGYIMQGSQFAVC 384
              ||   ||  ...|...|::......||
  Rat   356 --GF---RCYPQNPCQDPYVLTSENRCVC 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32373	NP_001261534.1	FXa_inhibition	124..158	CDD:291342	9/33 (27%)
		vWFA	<158..199	CDD:294047	18/40 (45%)
		FXa_inhibition	287..315	CDD:291342	12/32 (38%)
		CCP	340..398	CDD:153056	10/47 (21%)
Efemp1	NP_001012039.1	EGF_CA	173..>206	CDD:311536	12/58 (21%)
		EGF_CA	214..244	CDD:214542	16/30 (53%)
		cEGF	234..257	CDD:403760	10/23 (43%)
		Mediates interaction with TIMP3. /evidence=ECO:0000250	259..493		41/182 (23%)
		cEGF	274..297	CDD:403760	9/43 (21%)
		EGF_CA	294..333	CDD:214542	15/48 (31%)
		EGF_CA	334..378	CDD:214542	12/73 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000