DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32373 and B0393.5

DIOPT Version :9

Sequence 1:	NP_001261534.1	Gene:	CG32373 / 318000	FlyBaseID:	FBgn0052373	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_497982.2	Gene:	B0393.5 / 175632	WormBaseID:	WBGene00007170	Length:	1183	Species:	Caenorhabditis elegans

Alignment Length:	275	Identity:	74/275 - (26%)
Similarity:	105/275 - (38%)	Gaps:	83/275 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 RCRIDNGGCAHICNRSTHKCECYEGYTLNSTDLRSCNDIDECKESNGGC--SQVCNNLPGEFICT 185
            ||. .|..|      |...|.|.||:|   .|...|.|:|||:.....|  ..:|:|..|.|.||
Worm   452 RCD-QNAKC------SNGVCTCSEGFT---GDGFRCYDVDECEIPGAVCRDHSICSNTIGSFECT 506

  Fly   186 CNSGFEIDESDEKTCLDIDECAD-PELSWDCTAG--CKNLNGTYKCLPSLVGRVEPTDGDGFSPG 247
            |:.|:..::.   .|.|:|||.: |::..|...|  |.|.:||::||
Worm   507 CHGGYRFEDG---KCEDVDECRELPKICGDPNKGTKCINKDGTFECL------------------ 550

  Fly   248 EIVCKSGFKLSDDGSECQDINECDLADIDSDSWRMTYRYC--EHKCENTVGSYICHCPQGYHLLD 310
               ||.|:: .|..|||:|:|||...|.           |  ..:|.||.|.|.|.|..|:..:.
Worm   551 ---CKDGYE-GDPSSECRDVNECKNPDA-----------CGPNSQCTNTQGGYECECLAGFERIA 600

  Fly   311 DQNSCILDGSKLPPSKDAPVSQEAPRKDICPLFKGPANGKASCDKYLQNGFNYTRCNITCNAGYI 375
            :...|                   ..:|.|.:  .|.:..|.|    .|.....:|.  |..|::
Worm   601 EGAHC-------------------TDRDECAV--EPCHPAAIC----SNTRGSYKCE--CRDGFV 638

  Fly   376 MQGSQFAVCGHTGLW 390
            ..|.   .|..|.|:
Worm   639 GDGK---TCHETILY 650

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32373	NP_001261534.1	FXa_inhibition	124..158	CDD:291342	10/33 (30%)
		vWFA	<158..199	CDD:294047	14/42 (33%)
		FXa_inhibition	287..315	CDD:291342	9/29 (31%)
		CCP	340..398	CDD:153056	12/51 (24%)
B0393.5	NP_497982.2	NIDO	120..255	CDD:214712
		EGF_3	453..477	CDD:289699	10/33 (30%)
		EGF_CA	479..>512	CDD:284955	13/32 (41%)
		EGF_CA	520..563	CDD:284955	18/64 (28%)
		EGF_CA	565..606	CDD:214542	15/70 (21%)
		EGF_3	611..644	CDD:289699	9/43 (21%)
		NIDO	714..850	CDD:214712
		EGF_CA	912..952	CDD:214542
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159350
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930