DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32373 and Cd93

DIOPT Version :9

Sequence 1:	NP_001261534.1	Gene:	CG32373 / 318000	FlyBaseID:	FBgn0052373	Length:	486	Species:	Drosophila melanogaster
Sequence 2:	NP_034870.1	Gene:	Cd93 / 17064	MGIID:	106664	Length:	644	Species:	Mus musculus

Alignment Length:	329	Identity:	84/329 - (25%)
Similarity:	118/329 - (35%)	Gaps:	127/329 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 AKDNALY--CSN---GI--WLGLKPNCIKIGKGNTHSMKQKKMRCRIDNGGCAHIC--------- 135
            ||....|  |:.   ||  |....|.|:           ..|..|..:||||...|
Mouse   228 AKSETHYFLCNEKTPGIFHWGSSGPLCV-----------SPKFGCSFNNGGCQQDCFEGGDGSFR 281

  Fly   136 ------------------------NRST-------------HKCECYEGYTLNSTDLRSCNDIDE 163
                                    |..|             :.|.|..||.|:|:.:. |.||||
Mouse   282 CGCRPGFRLLDDLVTCASRNPCSSNPCTGGGMCHSVPLSENYTCRCPSGYQLDSSQVH-CVDIDE 345

  Fly   164 CKESNGGCSQVCNNLPGEFICTCNSGFEIDESDEKTCLDIDECADPELSWDCTAGCKNLNGTYKC 228
            |::|  .|:|.|.|..|.|.|.|..|::.....|:.|.|:||||  ..:..|..||.|.:|::.|
Mouse   346 CQDS--PCAQDCVNTLGSFHCECWVGYQPSGPKEEACEDVDECA--AANSPCAQGCINTDGSFYC 406

  Fly   229 LPSLVGRVEPTDGDGFSPGEIVCKSGFKLS-DDGSECQDINECDLADIDSDSWRMTYRYCEHKCE 292
                                 .||.|:.:| :|.::|:||:||      ||:   ....|:..|.
Mouse   407 ---------------------SCKEGYIVSGEDSTQCEDIDEC------SDA---RGNPCDSLCF 441

  Fly   293 NTVGSYICHCPQGYHLL-------------------------DDQNSCILDGSKLP--PSKDAPV 330
            ||.||:.|.||.|:.|.                         ||:....:..:::|  ||....|
Mouse   442 NTDGSFRCGCPPGWELAPNGVFCSRGTVFSELPARPPQKEDNDDRKESTMPPTEMPSSPSGSKDV 506

  Fly   331 SQEA 334
            |..|
Mouse   507 SNRA 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32373	NP_001261534.1	FXa_inhibition	124..158	CDD:291342	14/79 (18%)
		vWFA	<158..199	CDD:294047	17/40 (43%)
		FXa_inhibition	287..315	CDD:291342	13/52 (25%)
		CCP	340..398	CDD:153056
Cd93	NP_034870.1	CLECT	30..183	CDD:295302
		FXa_inhibition	261..297	CDD:291342	6/35 (17%)
		EGF	303..331	CDD:278437	4/27 (15%)
		cEGF	323..345	CDD:289433	9/22 (41%)
		EGF_CA	342..371	CDD:214542	15/30 (50%)
		vWFA	<376..419	CDD:294047	17/65 (26%)
		EGF_CA	424..456	CDD:214542	16/40 (40%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	473..508		6/34 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	605..644
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000