Protein Alignment Crag and SPCC297.05

DIOPT Version :9

• Sequence 1: NP_001162710.2
• Gene: Crag / 31800
• FlyBaseID: FBgn0025864
• Length: 1671
• Species: Drosophila melanogaster
• Sequence 2: NP_588362.1
• Gene: SPCC297.05 / 2539220
• PomBaseID: SPCC297.05
• Length: 973
• Species: Schizosaccharomyces pombe
• Alignment Length: 662
• Identity: 139/662 - (20%)
• Similarity: 219/662 - (33%)
• Gaps: 232/662 - (35%)

  Fly     6 IADYFVVAGMP------ENPQL----LQENSFNDSGRL-----------RAATTIEP-------- 41
            |||:|.:||:.      .|.|.    |.|::.:.|..:           |.:.|.|.
pombe     4 IADHFFLAGLSNGFVSVSNSQFRADRLDEDAISVSSSIIQNNTRKSPLKRVSITSESSFYKENTF 68

  Fly    42 -------ITDIGVYFPLLGEEVPEGYEILSHTPTGLQA-NLNHGSVRTTDCYIYFRRGKDRPPLV 98
                   ...:|...|.|     :.:...|:|||..:. :.:|.||.:.
pombe    69 AHHNTTGSNSVGPKKPFL-----DYHHSTSNTPTKKKKDSFDHASVTSL---------------- 112

  Fly    99 DIGVLYDGHERIMSDAEIVAETPGGRVANVNNSSAKTFLTYRRARADMPCNELVVTELCVIVQSK 163
                    |.|.:|                :|:|     |.|:..:..|.:|..|.:...:....
pombe   113 --------HRRSLS----------------SNTS-----TPRKYHSRKPYSEPSVIDKEHLQNRV 148

  Fly   164 GERAPHAFCLIYKTLNKGYVGSDVYLCYKKSM-----YRPKHISYKPEILLRY----------PT 213
            .....|....:|::          |:.|..::     ..|....|.|.:|.::          ||
pombe   149 SIGTTHTQNDLYQS----------YVAYPDALPLFAATHPFERRYPPSLLHQFPSSKDIKNETPT 203

  Fly   214 FDHTDFPLNLCPSVPLFCLPMGASLEAWPHVNGTEKRKPISPV--FSTFVLTVSDGTYKVYGSAL 276
            .|..|||    ..||:|..|...::          |...:.||  :.:|.|| ||....:||..:
pombe   204 IDRCDFP----NYVPMFAFPNDITI----------KESDVRPVSTYHSFALT-SDNNSHLYGICV 253

  Fly   277 -------------------------TFYED------------YDESKLSA-----EQKELLGWD- 298
                                     |..||            .:.||||:     ::|||.|.|
pombe   254 VVWVAMPQSMQNDLEKECEVWRANNTTVEDREVAEKLLSSLETERSKLSSLLLKMQEKELEGSDS 318

  Fly   299 ------------EE----------------------FGAQHSLHMIKAICLLSHHPFGDTFDK-W 328
                        ||                      .....:|.:..|..|||.|....:|.: |
pombe   319 IDPILLEKIDVCEENIILYTELLRPMRYKLPRFVHGLTNNRTLWIPNAYGLLSKHSHLQSFCRDW 383

  Fly   329 LKYLHRMVLYDVN------IP---------IPVERYITQLLDEVPFPAPS-IHLQLSSESNDRIL 377
            |    |:|...:.      ||         :.::.::..:..:||.|... :.||::....:...
pombe   384 L----RIVCSSIQAEDLDFIPSSDLNSLKSLNLQSFVKNICCDVPLPPKGLLQLQVNVGPLNLYA 444

  Fly   378 LTQPEDSPLPRSGAGFHILLQNLGTDNCLHVLLLALTEQKILIHSLRPATLTAVAEAIVSLLFPF 442
            ...|.:.....:....:.|.:.|...|.|.:...||.|.|::..|.....|...::|::.||:|.
pombe   445 FRSPVNEIPGWNDVDLYPLFRALSIPNILVLFEAALMEAKVIFLSENLGMLGYASQALLHLLYPL 509

  Fly   443 KWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRFFDLYEPPTD----VTCIDLDTNNISLCESQRHL 503
            .||..|||:.|..|.....||..|:||..|.||.:.:.|.|    |.| |||.|::|.......|
pombe   510 TWQGLYIPVLPRRLISCFEAPCSYIIGTLSYFFHMDDVPLDNIPLVVC-DLDKNSVSTFGKIVRL 573

  Fly   504 SPKLLPKRAARL 515
            |..|..|..|.|
pombe   574 SRSLRSKLQAHL 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Crag	NP_001162710.2	uDENN	189..279	CDD:214824	26/131 (20%)
		DENN	308..492	CDD:307995	54/204 (26%)
		dDENN	551..624	CDD:129037
		PPR repeat	808..837	CDD:276811
SPCC297.05	NP_588362.1	uDENN	174..256	CDD:214824	24/96 (25%)
		DENN	362..562	CDD:280329	54/204 (26%)
		dDENN	833..911	CDD:129037

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2678
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12296
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3728
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.130