DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32371 and BIM1

DIOPT Version :9

Sequence 1:	NP_729295.1	Gene:	CG32371 / 317999	FlyBaseID:	FBgn0052371	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_010932.1	Gene:	BIM1 / 856736	SGDID:	S000000818	Length:	344	Species:	Saccharomyces cerevisiae

Alignment Length:	302	Identity:	92/302 - (30%)
Similarity:	143/302 - (47%)	Gaps:	66/302 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 SRAEMLSWVNNTLKSQFFKVEELCTGAAYCQLMDILFARSIPMQRVKFRTNVEYEYIQNFKLLQG 87
            ||.|:|:|:|..|...:.|:||..|||||||:||.::. .:||.||||....|||:..|:|:||.
Yeast     8 SRTELLTWLNGLLNLNYKKIEECGTGAAYCQIMDSIYG-DLPMNRVKFNATAEYEFQTNYKILQS 71

  Fly    88 CFNKFVVDKIIPIDRLVKGRYQDNFEFLQWFRKFF-----DANYE---SREYDPVIARNGAMLGL 144
            ||::..::|.:.:|:|::.::|||.|||||.:|.:     ::.|:   .|:|.|:|..|.|
Yeast    72 CFSRHGIEKTVYVDKLIRCKFQDNLEFLQWLKKHWIRHKDESVYDPDARRKYRPIITNNSA---- 132

  Fly   145 GSPPMEAKLRKSVNKSNPQTKPTEESSAQTDRATTEPKNQVYKSNSENKTIEEASAQTDLAITEP 209
                     .|....||| |.....||..|..|.:......:.|...|.:.:.:..|..|...:.
Yeast   133 ---------TKPRTVSNP-TTAKRSSSTGTGSAMSGGLATRHSSLGINGSRKTSVTQGQLVAIQA 187

  Fly   210 ENQVHESQTKTTEKASAQTEKATTEPDSEGSI-EELRNYCKYVSRMKQERNFYLSKLRAID---H 270
            |                    .|...::.||: ||:..|...||.::.||.||.:|||.|:   |
Yeast   188 E--------------------LTKSQETIGSLNEEIEQYKGTVSTLEIEREFYFNKLRDIEILVH 232

  Fly   271 ICQ--------KYN--------SGRDRVIL---EKITKIIYS 293
            ..|        |:|        :|....:|   :|:..|:|:
Yeast   233 TTQDLINEGVYKFNDETITGHGNGNGGALLRFVKKVESILYA 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32371	NP_729295.1	CH	22..121	CDD:278723	45/97 (46%)
		BIM1	23..>269	CDD:227542	82/254 (32%)
		EB1	255..293	CDD:281288	16/59 (27%)
BIM1	NP_010932.1	BIM1	1..342	CDD:227542	92/302 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346084
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5217
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	133	1.000	Inparanoid score	I1228
Isobase	1	0.950	-	0	Normalized mean entropy	S1295
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000490
OrthoInspector	1	1.000	-	-		otm46835
orthoMCL	1	0.900	-	-		OOG6_100898
Panther	1	1.100	-	-	O	PTHR10623
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X303
TreeFam	1	0.960	-	-
	11	10.700