DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32371 and CG18190

DIOPT Version :9

Sequence 1:	NP_729295.1	Gene:	CG32371 / 317999	FlyBaseID:	FBgn0052371	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_611384.2	Gene:	CG18190 / 37179	FlyBaseID:	FBgn0034403	Length:	248	Species:	Drosophila melanogaster

Alignment Length:	180	Identity:	77/180 - (42%)
Similarity:	107/180 - (59%)	Gaps:	4/180 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 VNVRYTNKLSSNSSRAEMLSWVNNTLKSQFFKVEELCTGAAYCQLMDILFARSIPMQRVKFRTNV 74
            :.|..|:..:.|.||.:||.||||.:...|.|:||||:||||||:|:::|...|.::|||....:
  Fly     6 LTVALTSVNAENMSRHDMLQWVNNMVHGHFKKIEELCSGAAYCQMMEMIFPNCINLKRVKMTAKL 70

  Fly    75 EYEYIQNFKLLQGCFNKFVVDKIIPIDRLVKGRYQDNFEFLQWFRKFFDANYESREYDPVIARNG 139
            |:||:.|.:|.|..||:..:||.:|||||:|||:||||||||||:||||:.....|....:| |.
  Fly    71 EHEYLHNLRLFQEAFNRLKLDKTVPIDRLIKGRFQDNFEFLQWFKKFFDSQAPGLENIKSLA-NA 134

  Fly   140 AMLGLGSPPMEAKLRKSVNKSNPQTKP--TEESSAQTDRA-TTEPKNQVY 186
            .:.....|...||.|..||.::...|.  .|..:....|. ..|..||:|
  Fly   135 PLAKPIKPRQFAKERSPVNANDDALKELIDEMKNLSLKREDIMEASNQIY 184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32371	NP_729295.1	CH	22..121	CDD:278723	54/98 (55%)
		BIM1	23..>269	CDD:227542	74/167 (44%)
		EB1	255..293	CDD:281288
CG18190	NP_611384.2	CH	19..>92	CDD:278723	34/72 (47%)
CG18190	NP_611384.2	EB1	184..216	CDD:281288	1/1 (100%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468771
Domainoid	1	1.000	103	1.000	Domainoid score	I2253
eggNOG	1	0.900	-	-		E1_COG5217
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D100079at50557
OrthoFinder	1	1.000	-	-		FOG0000490
OrthoInspector	1	1.000	-	-		mtm1038
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10623
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X303
	9	8.850