DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32371 and mal3

DIOPT Version :9

Sequence 1:	NP_729295.1	Gene:	CG32371 / 317999	FlyBaseID:	FBgn0052371	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_593678.1	Gene:	mal3 / 2542123	PomBaseID:	SPAC18G6.15	Length:	308	Species:	Schizosaccharomyces pombe

Alignment Length:	276	Identity:	76/276 - (27%)
Similarity:	128/276 - (46%)	Gaps:	40/276 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 NSSRAEMLSWVNNTLKSQFFKVEELCTGAAYCQLMDILFARSIPMQRVKFRTNVEYEYIQNFKLL 85
            :.||.|:|:|:|........::|:...|.|..|:.|.:: :.||:::|.|..|.||:||.|:|:|
pombe     2 SESRQELLAWINQVTSLGLTRIEDCGKGYAMIQIFDSIY-QDIPLKKVNFECNNEYQYINNWKVL 65

  Fly    86 QGCFNKFVVDKIIPIDRLVKGRYQDNFEFLQWFRKFFDANYESREYDPVIARNGAMLGLGSPPME 150
            |..|.|..:||::..:||.:.:.|||.||:||.::|:|..|...:|| .:||.|..    .|...
pombe    66 QQVFLKKGIDKVVDPERLSRCKMQDNLEFVQWAKRFWDQYYPGGDYD-ALARRGNR----GPANT 125

  Fly   151 AKLRKSVNKSNPQTKPTEESSAQTDRATTEPKNQVYKSNSENKTIEEASAQTDLAITEPENQVHE 215
            ..:..|...:.|..:....|.:.|...|....|....|::.|......:.|....||..|.|::|
pombe   126 RVMNSSAGATGPSRRRQVSSGSSTPSMTKSSANNNNVSSTANTAAVLRAKQAQQQITSLETQLYE 190

  Fly   216 SQTKTTEKASAQTEKATTEPDSEGSIEELRNYCKYVSRMKQERNFYLSKLRAIDHICQKYNSGRD 280
                                     :.|.      :..:::||:||.:|||.|:.:.|.:.:...
pombe   191 -------------------------VNET------MFGLERERDFYFNKLREIEILVQTHLTTSP 224

  Fly   281 ---RVILEKITKIIYS 293
               ..:||:|..|:||
pombe   225 MSMENMLERIQAILYS 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32371	NP_729295.1	CH	22..121	CDD:278723	37/98 (38%)
		BIM1	23..>269	CDD:227542	68/245 (28%)
		EB1	255..293	CDD:281288	13/40 (33%)
mal3	NP_593678.1	BIM1	1..308	CDD:227542	76/276 (28%)
		CH	3..81	CDD:278723	28/78 (36%)
		EB1	199..240	CDD:281288	13/40 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	89	1.000	Domainoid score	I2088
eggNOG	1	0.900	-	-		E1_COG5217
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	155	1.000	Inparanoid score	I1277
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000490
OrthoInspector	1	1.000	-	-		otm47289
orthoMCL	1	0.900	-	-		OOG6_100898
Panther	1	1.100	-	-	O	PTHR10623
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X303
TreeFam	1	0.960	-	-
	10	9.820