Protein Alignment CG32371 and MAPRE2

DIOPT Version :10

• Sequence 1: NP_729295.1
• Gene: CG32371 / 317999
• FlyBaseID: FBgn0052371
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_055083.1
• Gene: MAPRE2 / 10982
• HGNCID: 6891
• Length: 327
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 99/289 - (34%)
• Similarity: 157/289 - (54%)
• Gaps: 40/289 - (13%)

  Fly    10 VNVRYTNKLSSNSSRAEMLSWVNNTLKSQFFKVEELCTGAAYCQLMDILFARSIPMQRVKFRTNV 74
            |||..|:......||.::::|||:.:...:.|||:||:||||||.||:||...|.:::|||:..:
Human    46 VNVYSTSITQETMSRHDIIAWVNDIVSLNYTKVEQLCSGAAYCQFMDMLFPGCISLKKVKFQAKL 110

  Fly    75 EYEYIQNFKLLQGCFNKFVVDKIIPIDRLVKGRYQDNFEFLQWFRKFFDANYESREYDPVIARNG 139
            |:|||.||||||..|.:..|||:||:::|||||:|||.:|:|||:||:||||:.:|||||.||.|
Human   111 EHEYIHNFKLLQASFKRMNVDKVIPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEARQG 175

  Fly   140 AMLGLGSPPMEA-----KLRKSVNKSNPQTKPTEESSAQTDRATTEPKNQVYKSNSENKTIEEAS 199
            ..   ..||.:.     .|.|..:.:|..|....:||......:|..:....|..|.:.:..::.
Human   176 QD---AIPPPDPGEQIFNLPKKSHHANSPTAGAAKSSPAAKPGSTPSRPSSAKRASSSGSASKSD 237

  Fly   200 AQTDLAITEPENQVHESQTKTTEKASAQTEKATTEPDSEGSIEELRNYCKYVSRMKQERNFYLSK 264
            ...:..:.:...|||..:...                 ||              :::||:||..|
Human   238 KDLETQVIQLNEQVHSLKLAL-----------------EG--------------VEKERDFYFGK 271

  Fly   265 LRAIDHICQKYNSGRDRVILEKITKIIYS 293
            ||.|:.:||::....|.:: :::..|:|:
Human   272 LREIELLCQEHGQENDDLV-QRLMDILYA 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32371	NP_729295.1	BIM1	23..>269	CDD:227542	89/250 (36%)
		EB1	254..293	CDD:460870	12/38 (32%)
MAPRE2	NP_055083.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		BIM1	59..313	CDD:227542	95/276 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	171..240		14/71 (20%)
		DCTN1-binding	187..327		27/145 (19%)
		APC-binding	259..302		15/56 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	299..327		0/1 (0%)