DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG32371 and Mapre3

DIOPT Version :9

Sequence 1:NP_729295.1 Gene:CG32371 / 317999 FlyBaseID:FBgn0052371 Length:294 Species:Drosophila melanogaster
Sequence 2:NP_579928.1 Gene:Mapre3 / 100732 MGIID:2140967 Length:281 Species:Mus musculus


Alignment Length:291 Identity:110/291 - (37%)
Similarity:164/291 - (56%) Gaps:43/291 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 VNVRYTNKLSSNSSRAEMLSWVNNTLKSQFFKVEELCTGAAYCQLMDILFARSIPMQRVKFRTNV 74
            |||..|:..|.|.||.:||:|||::|...:.|:|:||:||||||.||:||...:.:::|||:..:
Mouse     3 VNVYSTSVTSENLSRHDMLAWVNDSLHLNYTKIEQLCSGAAYCQFMDMLFPGCVHLRKVKFQAKL 67

  Fly    75 EYEYIQNFKLLQGCFNKFVVDKIIPIDRLVKGRYQDNFEFLQWFRKFFDANYESREYDPVIARNG 139
            |:|||.|||:||..|.|..||||||:::||||::||||||:|||:|||||||:.::|:|::||.|
Mouse    68 EHEYIHNFKVLQAAFKKMGVDKIIPVEKLVKGKFQDNFEFIQWFKKFFDANYDGKDYNPLLARQG 132

  Fly   140 AMLGLGSPPMEA-----KLRKSVNKSNPQ-TKPTEESSAQTD-RATTEPKNQVYKSNSENKTIEE 197
            .  .:..||...     |.:|.:..:.|| |.||...:.||. |.:......:.:.|..:     
Mouse   133 Q--DVAPPPNPGDQIFNKSKKLIGTAVPQRTSPTGPKNMQTSGRLSNVAPPCILRKNPPS----- 190

  Fly   198 ASAQTDLAITEPENQVHESQTKTTEKASAQTEKATTEPDSEGSIEELRNYCKYVSRMKQERNFYL 262
                       ..|..||:..:..|..                 ::|.:....|..:::||:||.
Mouse   191 -----------ARNGGHEADAQILELN-----------------QQLLDLKLTVDGLEKERDFYF 227

  Fly   263 SKLRAIDHICQKYNSGRDRVILEKITKIIYS 293
            ||||.|:.|||::.|....|| ..|..|:|:
Mouse   228 SKLRDIELICQEHESENSPVI-SGIIGILYA 257

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG32371NP_729295.1 CH 22..121 CDD:278723 55/98 (56%)
BIM1 23..>269 CDD:227542 94/252 (37%)
EB1 255..293 CDD:281288 17/37 (46%)
Mapre3NP_579928.1 BIM1 16..279 CDD:227542 104/278 (37%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 157..181 8/23 (35%)
DCTN1-binding. /evidence=ECO:0000250 217..281 18/42 (43%)
APC-binding. /evidence=ECO:0000250 217..260 18/42 (43%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 260..281
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167849192
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5217
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1237523at2759
OrthoFinder 1 1.000 - - FOG0000490
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100898
Panther 1 1.100 - - O PTHR10623
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X303
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
109.710

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