DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tut and rbm19

DIOPT Version :9

Sequence 1:	NP_729346.1	Gene:	tut / 317996	FlyBaseID:	FBgn0052364	Length:	230	Species:	Drosophila melanogaster
Sequence 2:	XP_012825334.1	Gene:	rbm19 / 733862	XenbaseID:	XB-GENE-922190	Length:	920	Species:	Xenopus tropicalis

Alignment Length:	238	Identity:	44/238 - (18%)
Similarity:	80/238 - (33%)	Gaps:	58/238 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ESKYCTSQVNGTITITTRKVLDENLKSLLDEGKGELFLSCI----PRNHSCSPRWIVEVASELGE 64
            ::...||:.....|..|::.:.|......:|.:.|....|.    ..|.|.|...:.|:.|::|.
Frog   656 QTNQVTSEEQEADTADTKEEVKEMEVEDQEEDEEEALPGCTLFIKNLNFSTSEETLKEIFSKVGA 720

  Fly    65 V--YIMRYKIDFSGN--SRGYAYLQYINVDLKESAMQYLPMRFRQLCMC---------------L 110
            |  ..:..|.|.||:  ..|:.:::|...:..:.|:       |||..|               :
Frog   721 VKSCSISKKKDKSGSLLPMGFGFVEYTKPEQAQKAL-------RQLQKCTVDGHQVEIKLSERAI 778

  Fly   111 RVEPSTNNRELVLKNVESSLRPWQVYQEMLKIHPF-TIVRVYEYQLDQF---------------- 158
            |...||..::...|..:||       :.:::..|| ..||........|
Frog   779 RAATSTERKKQNSKKQQSS-------KILVRNVPFQATVREIRELFSTFGELKTVRLPKKMAGTG 836

  Fly   159 ----FYIFEYRNNDSAASAHQRVRNSIRKFGEHAHISWLTAEN 197
                |...::.....|..|...:.:|...:|....:.|...|:
Frog   837 SHRGFGFVDFVTKQDAKRAFSALCHSTHLYGRRLVLEWAETED 879

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tut	NP_729346.1	RRM1_hnRNPR_like	36..115	CDD:240695	21/101 (21%)
tut	NP_729346.1	DUF3388	<127..169	CDD:288701	8/62 (13%)
rbm19	XP_012825334.1	RRM1_RBM19	2..77	CDD:241008
		RRM2_RMB19	279..350	CDD:240946
		RRM3_RBM19	384..462	CDD:241011
		RRM4_RBM19	570..641	CDD:241013
		RRM5_RBM19_like	695..774	CDD:240764	19/85 (22%)
		RRM6_RBM19	797..875	CDD:241015	11/84 (13%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910