DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tut and A1cf

DIOPT Version :9

Sequence 1:	NP_729346.1	Gene:	tut / 317996	FlyBaseID:	FBgn0052364	Length:	230	Species:	Drosophila melanogaster
Sequence 2:	NP_001074543.1	Gene:	A1cf / 69865	MGIID:	1917115	Length:	595	Species:	Mus musculus

Alignment Length:	168	Identity:	44/168 - (26%)
Similarity:	85/168 - (50%)	Gaps:	14/168 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 ELFLSCIPRNHSCSPRWIVEVASELGEVYIMRYKIDFSGNSRGYAYLQYINVDLKESAMQYL--- 99
            |:|:..:||:  .....::.:..::|::|.||..:||:||:||||::.:.|....::|::.|
Mouse    57 EIFIGKLPRD--LFEDELIPLCEKIGKIYEMRLMMDFNGNNRGYAFVTFSNKQEAKNAIKQLNNY 119

  Fly   100 PMRFRQLCMCLRVEPSTNNRELVLKNVESSLRPWQVYQEMLKIHPFTI-VRVYEYQLDQF----F 159
            .:|..:|   |.|..|.:|..|.:..:..:.:..::..||.|:....: |.||....|:.    |
Mouse   120 EIRTGRL---LGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGF 181

  Fly   160 YIFEYRNNDSAASAHQR-VRNSIRKFGEHAHISWLTAE 196
            ...||.::.:||.|.:| :...|:.:|....:.|...|
Mouse   182 AFVEYESHRAAAMARRRLLPGRIQLWGHPIAVDWAEPE 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tut	NP_729346.1	RRM1_hnRNPR_like	36..115	CDD:240695	23/79 (29%)
tut	NP_729346.1	DUF3388	<127..169	CDD:288701	10/46 (22%)
A1cf	NP_001074543.1	hnRNP-R-Q	2..595	CDD:273732	44/168 (26%)
A1cf	NP_001074543.1	Required for nuclear localization. /evidence=ECO:0000250\|UniProtKB:Q9NQ94	360..409
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0117
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810