DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tut and rbm46

DIOPT Version :9

Sequence 1:	NP_729346.1	Gene:	tut / 317996	FlyBaseID:	FBgn0052364	Length:	230	Species:	Drosophila melanogaster
Sequence 2:	NP_001073493.2	Gene:	rbm46 / 566042	ZFINID:	ZDB-GENE-061013-298	Length:	523	Species:	Danio rerio

Alignment Length:	195	Identity:	46/195 - (23%)
Similarity:	90/195 - (46%)	Gaps:	33/195 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 ELFLSCIPRNHSCSPRWIVEVASELGEVYIMRYKIDFSGNSRGYAYLQYINVDLKESAMQYL--- 99
            |:|:..|||:  .....:|.|..:.|.:|..|..::|||.:||||::.|...:..:.|:|.|
Zfish    59 EVFVGKIPRD--MYEDELVPVFEQAGHIYEFRLMMEFSGENRGYAFVMYTTREKAQRAIQLLDNY 121

  Fly   100 ---PMRFRQLCMCLRVEPSTNNRELVLKNVESSLRPWQVYQEMLKIHPFTI-VRVYEYQLDQF-- 158
               |.:|..:|:      |.:|..|.:.::....:..::.:||:|:....: |.||...:|:.
Zfish   122 EIRPGKFIGVCV------SLDNCRLFIGSIPKDKKKEEIQEEMMKVTEGVMDVIVYPSAVDRMKN 180

  Fly   159 --FYIFEYRNNDSAASAHQR-VRNSIRKFGEHAHISWLTAENILSRASGSFCFQREVSQNRTRRV 220
              |...||.::.:||.|.:: :..:.:.:|....:.|...|             :|:.:...:||
Zfish   181 RGFAFVEYESHKAAAMARRKLIPGTFQLWGHTIQVDWAEPE-------------KELDEETMQRV 232

Fly 221 220
Zfish 233 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tut	NP_729346.1	RRM1_hnRNPR_like	36..115	CDD:240695	24/82 (29%)
tut	NP_729346.1	DUF3388	<127..169	CDD:288701	10/46 (22%)
rbm46	NP_001073493.2	RRM1_RBM46	58..134	CDD:240928	24/82 (29%)
		RRM2_RBM46	136..220	CDD:240936	17/83 (20%)
		RRM_SF	225..305	CDD:302621	2/8 (25%)
		DND1_DSRM	392..463	CDD:291380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0117
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810