DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tut and DND1

DIOPT Version :9

Sequence 1:	NP_729346.1	Gene:	tut / 317996	FlyBaseID:	FBgn0052364	Length:	230	Species:	Drosophila melanogaster
Sequence 2:	NP_919225.1	Gene:	DND1 / 373863	HGNCID:	23799	Length:	353	Species:	Homo sapiens

Alignment Length:	170	Identity:	38/170 - (22%)
Similarity:	73/170 - (42%)	Gaps:	26/170 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 ELFLSCIPRN---HSCSPRWIVEVASELGEVYIMRYKIDFSGNSRGYAYLQYINVDLKESAMQYL 99
            |:|:..:|::   |.     ::.:...:|.:|..|..:.|||.:||:||.:|.:....::|:..|
Human    59 EVFIGRLPQDVYEHQ-----LIPLFQRVGRLYEFRLMMTFSGLNRGFAYARYSSRRGAQAAIATL 118

  Fly   100 ---PMRFRQLCMCLRVEPSTNNRELVLKNVESSLRPWQVYQEMLKIHPFTIVRVYEYQL------ 155
               |:  |..|..| |..||...||.:..:..:|....:...:..:.|    .:.|.:|
Human   119 HNHPL--RPSCPLL-VCRSTEKCELSVDGLPPNLTRSALLLALQPLGP----GLQEARLLPSPGP 176

  Fly   156 -DQFFYIFEYRNNDSAASAHQR-VRNSIRKFGEHAHISWL 193
             .....:.::.::.:||.|.:. |.......||...:.||
Human   177 APGQIALLKFSSHRAAAMAKKALVEGQSHLCGEQVAVEWL 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tut	NP_729346.1	RRM1_hnRNPR_like	36..115	CDD:240695	22/82 (27%)
tut	NP_729346.1	DUF3388	<127..169	CDD:288701	4/48 (8%)
DND1	NP_919225.1	LSM_int_assoc	18..>219	CDD:330438	38/170 (22%)
DND1	NP_919225.1	DND1_DSRM	253..333	CDD:317152
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0117
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810