DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tut and A1CF

DIOPT Version :9

Sequence 1:	NP_729346.1	Gene:	tut / 317996	FlyBaseID:	FBgn0052364	Length:	230	Species:	Drosophila melanogaster
Sequence 2:	NP_001185748.1	Gene:	A1CF / 29974	HGNCID:	24086	Length:	602	Species:	Homo sapiens

Alignment Length:	208	Identity:	50/208 - (24%)
Similarity:	89/208 - (42%)	Gaps:	54/208 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 LKSLLDEGKG--------------------ELFLSCIPRNHSCSPRWIVEVASELGEVYIMRYKI 72
            |::||::..|                    |:|:..:||:  .....::.:..::|::|.||..:
Human    35 LQTLLEKENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRD--LFEDELIPLCEKIGKIYEMRMMM 97

  Fly    73 DFSGNSRGYAYLQYIN-VDLKESAMQ---YLPMRFRQLCMCLRVE---------PSTNNRELVLK 124
            ||:||:||||::.:.| |:.|.:..|   |.....|.|.:|..|:         |.|..||
Human    98 DFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTKKRE---- 158

  Fly   125 NVESSLRPWQVYQEMLKIHPFTI-VRVYEYQLDQF----FYIFEYRNNDSAASAHQR-VRNSIRK 183
                     ::..||.|:....: |.||....|:.    |...||.::.:||.|.:: :...|:.
Human   159 ---------EILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQL 214

  Fly   184 FGEHAHISWLTAE 196
            :|....:.|...|
Human   215 WGHGIAVDWAEPE 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tut	NP_729346.1	RRM1_hnRNPR_like	36..115	CDD:240695	26/111 (23%)
tut	NP_729346.1	DUF3388	<127..169	CDD:288701	10/46 (22%)
A1CF	NP_001185748.1	hnRNP-R-Q	29..602	CDD:273732	50/208 (24%)
		RRM1_ACF	63..140	CDD:240930	24/78 (31%)
		RRM2_ACF	142..226	CDD:240934	20/96 (21%)
		RRM3_ACF	231..313	CDD:240942
		DND1_DSRM	455..531	CDD:291380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0117
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810