DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tut and Dnd1

DIOPT Version :9

Sequence 1:	NP_729346.1	Gene:	tut / 317996	FlyBaseID:	FBgn0052364	Length:	230	Species:	Drosophila melanogaster
Sequence 2:	NP_775559.2	Gene:	Dnd1 / 213236	MGIID:	2447763	Length:	352	Species:	Mus musculus

Alignment Length:	198	Identity:	48/198 - (24%)
Similarity:	88/198 - (44%)	Gaps:	26/198 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 ELFLSCIPRN---HSCSPRWIVEVASELGEVYIMRYKIDFSGNSRGYAYLQYINVDLKESAMQYL 99
            |:::..:|::   |.     ::.:...:|.:|..|..:.|||.:||:||.:|.:....::|:..|
Mouse    59 EVYIGRLPQDVYEHQ-----LIPLFQRVGRLYEFRLMMTFSGLNRGFAYARYSSRRGAQAAIATL 118

  Fly   100 -PMRFRQLCMCLRVEPSTNNRELVLKNVESSLRPWQVYQEMLKIHPF------TIVRVYEYQLDQ 157
             ..:.|..|..| |..||...||.:..:..||....:   :|.:.||      |::.........
Mouse   119 HNHQLRPSCQLL-VCRSTEKCELTVDGLPLSLNRRAL---LLALQPFGPCLQETLLLPSPGSAPS 179

  Fly   158 FFYIFEYRNNDSAASAHQR-VRNSIRKFGEHAHISWL---TAENILSRASG-SFCFQR-EVSQ-N 215
            ...:.::..:.:||.|.:. |....|..||...:.||   ..::...:.:| |..|.| :||| .
Mouse   180 QIALLKFSTHRAAAMAKKALVEGQSRLCGEQVAVEWLKPDLKQHFRQQLAGPSLRFLRPDVSQLT 244

  Fly   216 RTR 218
            :||
Mouse   245 QTR 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tut	NP_729346.1	RRM1_hnRNPR_like	36..115	CDD:240695	20/80 (25%)
tut	NP_729346.1	DUF3388	<127..169	CDD:288701	6/47 (13%)
Dnd1	NP_775559.2	RRM1_DND1	57..134	CDD:240931	20/80 (25%)
		RRM_SF	136..218	CDD:302621	17/84 (20%)
		DND1_DSRM	253..333	CDD:291380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0117
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810