DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tut and hrpr-1

DIOPT Version :9

Sequence 1:	NP_729346.1	Gene:	tut / 317996	FlyBaseID:	FBgn0052364	Length:	230	Species:	Drosophila melanogaster
Sequence 2:	NP_493049.2	Gene:	hrpr-1 / 173086	WormBaseID:	WBGene00002000	Length:	611	Species:	Caenorhabditis elegans

Alignment Length:	250	Identity:	52/250 - (20%)
Similarity:	101/250 - (40%)	Gaps:	73/250 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ESKYCTSQV---------NGTITITTRKVLD----ENLKSLLD---------------------- 33
            :|.|.||.:         .|...:|:.|:::    ..||:||:
Worm   124 KSLYVTSLIRSFKDRCRQQGAAAVTSGKLINGPELAALKNLLETTGYTIEVTIGQRKFGGPPPDW 188

  Fly    34 -------EGKG-ELFLSCIPRNHSCSPRWIVEVASELGEVYIMRYKID-FSGNSRGYAYLQYIN- 88
                   .|:| |:::..||.:  .....:|.:..:.|:::.:|..:| .||.|||||::.|.|
Worm   189 EGPATGPAGQGHEIYVGHIPTD--VFEDTLVPLFEKSGKIWDLRLMMDPMSGASRGYAFVTYCNK 251

  Fly    89 VDLKESAMQY--------LPMRFRQLCMCLRVEPSTNNRELVLKNVESSLRPWQVYQEMLKIHPF 145
            .|...:|..|        .|         |:|..|..|..|.:.|:..:....::.:| ||.|..
Worm   252 EDAAAAAKTYDGHEISTGKP---------LKVNVSIANTRLFIGNIPKTKSKDEILEE-LKTHAE 306

  Fly   146 TIVRVYEYQL-------DQFFYIFEYRNNDSAASAHQRV-RNSIRKFGEHAHISW 192
            .:|.|..|.:       ::.|...::.::.:|:...::: ::.||.|....::.|
Worm   307 GVVDVIVYSVPDNEKIKNRGFCFVDFIDHKTASDIKRKIAQHKIRPFNADVYVDW 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tut	NP_729346.1	RRM1_hnRNPR_like	36..115	CDD:240695	23/89 (26%)
tut	NP_729346.1	DUF3388	<127..169	CDD:288701	8/48 (17%)
hrpr-1	NP_493049.2	RRM1_hnRNPR_like	199..277	CDD:240695	23/88 (26%)
		RRM2_hnRNPR_like	280..362	CDD:240696	15/82 (18%)
		RRM3_hnRNPR_like	376..445	CDD:240697
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910