DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12081 and AT1G18610

DIOPT Version :9

Sequence 1:	NP_001259343.1	Gene:	CG12081 / 31799	FlyBaseID:	FBgn0030053	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001321087.1	Gene:	AT1G18610 / 838442	AraportID:	AT1G18610	Length:	556	Species:	Arabidopsis thaliana

Alignment Length:	386	Identity:	112/386 - (29%)
Similarity:	169/386 - (43%)	Gaps:	58/386 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 GP-QRVNHA--AVGVGDFIYSFGGYCTGYD-YRYNEPIDVHALNAHTMRWTLVPQQLDDAGVPLK 70
            || :|..|.  |:..|.|:|.||||  |.| .:.|:   ||..:|....||   |.:.: |.|
plant    21 GPGKRWGHTCNAIKGGSFLYVFGGY--GRDNCQTNQ---VHVFDAAKQIWT---QPMIN-GTP-- 74

  Fly    71 YPLVPFQRYGHTVVAYKDRIYIWGGRNDENLCNTLYCFDPKTAQWSRPQVTGCLPGARDGHSACV 135
                |..|..|:.....|.::::||.:..|....||..|..:..|..|.|.|..|.||:||||.:
plant    75 ----PPPRDSHSCTTVGDNLFVFGGTDGVNPLKDLYILDTSSHTWKCPSVRGEGPEAREGHSATL 135

  Fly   136 IGNSMYIFGGF--VDEINE--FSSDVHSLNLDTMEWRYVQTFGVPPSYRDFHASVAYEQERMYIF 196
            :|..:::|||.  ...|||  :.:||:..|.:|..|:...|.|.|||.||.|:..:: :.::.:.
plant   136 VGKRLFVFGGCGKSSGINEEIYYNDVYIFNTETFVWKRAVTIGNPPSARDSHSCSSW-KNKLVVI 199

  Fly   197 GGRGDKHSPYHSQEETYCHEIVYLDMKTKVWHRPFTAGKVPVGRRSHSMFVYNKLIYVFGGYNGL 261
            ||. |.|       :.|..::..||..|.:|....|:|::...|..|......:..:||||:..
plant   200 GGE-DGH-------DYYLSDVHILDTDTLIWKELNTSGQLLTPRAGHVTVSLGRNFFVFGGFTD- 255

  Fly   262 LDQHFNDLYTFDPRTKLWNLIRANGKAPTARRRQCAIVMGTRMFLFGGTSPRSGSSSSPAAVSPT 326
            ....::|||..|..|.:|:.:...|:.|:||                       .||:.|.:.|
plant   256 AQNLYDDLYVLDVDTCIWSKVLTMGEGPSAR-----------------------FSSAGACLDP- 296

  Fly   327 QETGGAAAAGGVVPPGVALIDYSDLHV-LDFEPTLKTLATMVVLKHQLDISGLPRSFRSDL 386
            .:.|.....||......||.|...|.. |.::........|:.||.||.|....:|..|.|
plant   297 HKAGFLVIVGGCNKNLEALDDMFYLQTGLGYDARFDQNVGMLSLKKQLKIKCQEQSHASSL 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12081	NP_001259343.1	KELCH repeat	13..69	CDD:276965	20/58 (34%)
		Kelch_6	13..60	CDD:290672	18/49 (37%)
		KELCH repeat	78..125	CDD:276965	13/46 (28%)
		Kelch_1	78..117	CDD:279660	10/38 (26%)
		KELCH repeat	128..170	CDD:276965	17/45 (38%)
		Kelch_3	137..188	CDD:290151	20/54 (37%)
		KELCH repeat	180..236	CDD:276965	14/55 (25%)
		Kelch_3	192..248	CDD:290151	13/55 (24%)
		Kelch_5	237..276	CDD:290565	10/38 (26%)
AT1G18610	NP_001321087.1	PLN02193	<7..320	CDD:177844	101/347 (29%)
		KELCH repeat	25..69	CDD:276965	19/51 (37%)
		KELCH repeat	78..125	CDD:276965	13/46 (28%)
		KELCH repeat	128..173	CDD:276965	17/44 (39%)
		KELCH repeat	184..232	CDD:276965	14/56 (25%)
		KELCH repeat	235..281	CDD:276965	12/46 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H14290
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001118
OrthoInspector	1	1.000	-	-		otm2855
orthoMCL	1	0.900	-	-		OOG6_102848
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.770