DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12081 and AT5G04420

DIOPT Version :9

Sequence 1:	NP_001259343.1	Gene:	CG12081 / 31799	FlyBaseID:	FBgn0030053	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001031832.1	Gene:	AT5G04420 / 830321	AraportID:	AT5G04420	Length:	514	Species:	Arabidopsis thaliana

Alignment Length:	371	Identity:	97/371 - (26%)
Similarity:	158/371 - (42%)	Gaps:	61/371 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 RVNHAAVGVGDFIYSFGGYCTGYDYRYNEPIDVHALNAHTMRWTLVP-----------QQLDDAG 66
            |..||||.|.:.:|..||...|   ||..  ||...:..::.|:.:.           |:.|.:.
plant    35 RYKHAAVVVDEKLYIVGGSRNG---RYLS--DVQVFDLRSLTWSSLKLKTESSSADNIQEDDGSS 94

  Fly    67 VPLKYPLVPFQRYGHTVVAYKDRIYIWGGRNDENLCNTLYCF-DPKTAQWSRPQVTGCLPGARDG 130
            :...:|.:.    .|.::.:.:::.:.||.:.::..|.|..| |.:|.......|.|.:|.:|.|
plant    95 LREAFPAIS----DHRMIKWGNKLLLIGGHSKKSSDNMLVRFIDLETHSCGVIDVFGNVPASRGG 155

  Fly   131 HSACVIGNSMYIFGGFVDEINEFSSDVHSLNLDTMEWRYVQTFGVPPSYRDFHASVAYEQERMYI 195
            ||..::|:.:.:||| .|:.....:|:|.|:|:||.|..|:|....|..|..|.:..:....:.|
plant   156 HSITLVGSRVLVFGG-EDKNRRLLNDLHVLHLETMTWDVVETKQTRPVPRFDHTAATHSDRYLLI 219

  Fly   196 FGGRGDKHSPYHSQEETYCHEIVYLDMKTKVWHRPFTAGKVPVGRRSHSMFVYNKLIYVFGG--- 257
            ||  |..||.::|       ::..||::|..|.:|...|.|...|..|:....::..|:.||
plant   220 FG--GCSHSIFYS-------DLHILDLQTMEWSQPHVQGDVVTPRAGHAGITIDENWYIVGGGDN 275

  Fly   258 YNGLLDQHFNDLYTFDPRTKL-WNL-IRANGKAPTARR--RQC-AIVMGTRMFL-FGGTSP---- 312
            ..|.|:....::      :|| |:. .....:.|.|..  ..| |.|.|..:.: |||.:.
plant   276 STGCLETLVLNM------SKLVWSTSTHVEARHPLASEGLSVCSASVFGENILVAFGGYNGKYNN 334

  Fly   313 -------RSGSSSSPAAV-SPTQETGGAAAAGGVVPPGVALIDYSD 350
                   :.|.||.|... ||   ...||||.......:|..|.||
plant   335 DIFVMRLKPGESSHPKIFKSP---AAAAAAASVTAAYAIAKSDKSD 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12081	NP_001259343.1	KELCH repeat	13..69	CDD:276965	17/66 (26%)
		Kelch_6	13..60	CDD:290672	15/57 (26%)
		KELCH repeat	78..125	CDD:276965	10/47 (21%)
		Kelch_1	78..117	CDD:279660	8/39 (21%)
		KELCH repeat	128..170	CDD:276965	16/41 (39%)
		Kelch_3	137..188	CDD:290151	17/50 (34%)
		KELCH repeat	180..236	CDD:276965	15/55 (27%)
		Kelch_3	192..248	CDD:290151	16/55 (29%)
		Kelch_5	237..276	CDD:290565	7/41 (17%)
AT5G04420	NP_001031832.1	Kelch_1	34..75	CDD:366584	15/44 (34%)
		KELCH repeat	35..128	CDD:276965	21/101 (21%)
		PLN02193	<147..>336	CDD:177844	56/204 (27%)
		KELCH repeat	153..201	CDD:276965	18/48 (38%)
		KELCH repeat	204..243	CDD:276965	12/47 (26%)
		KELCH repeat	255..294	CDD:276965	10/44 (23%)
		Smc	395..>503	CDD:224117
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D933937at2759
OrthoFinder	1	1.000	-	-		FOG0001118
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920