DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG12081 and NSP1

DIOPT Version :9

Sequence 1:NP_001259343.1 Gene:CG12081 / 31799 FlyBaseID:FBgn0030053 Length:403 Species:Drosophila melanogaster
Sequence 2:NP_001030709.1 Gene:NSP1 / 820887 AraportID:AT3G16400 Length:470 Species:Arabidopsis thaliana


Alignment Length:376 Identity:89/376 - (23%)
Similarity:151/376 - (40%) Gaps:86/376 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 WTVHLDGGPQRVNHAAVGVGDF--IYSF-------------------GGYCTGYDYRYNEPIDVH 46
            :.|:::|..::||.....:..|  |.:|                   ||...|:..|..:.:  |
plant    73 YIVYVEGYREKVNDMTSEMITFLSIKTFKGKTSHPIEKRPGVKFVLHGGKIVGFHGRSTDVL--H 135

  Fly    47 ALNAHTM---------RWTLVPQQLDDAGVPLKYPLVPFQRYGHTVVAYKDRIYIWGGRNDEN-- 100
            :|.|:..         :|..|.|:.:..|:          |..|.:....::||.:||....|  
plant   136 SLGAYVSLSSTIKLLGKWIKVEQKGEGPGL----------RCSHGIAQVGNKIYSFGGEFTPNQP 190

  Fly   101 LCNTLYCFDPKTAQWSRPQVTGCLPGARDGHSACV------IGNSMYIFGGFVDEINEFSSDVHS 159
            :...||.||.:|..||....||.:|     |.:|:      :|:::|:||| .|...:::. .:|
plant   191 IDKHLYVFDLETRTWSISPATGDVP-----HLSCLGVRMVSVGSTLYVFGG-RDASRQYNG-FYS 248

  Fly   160 LNLDTMEWRYVQTFGVPPSYRDFHASVAYEQERMYIFGG-----RGDKHSPYHSQEETYCHEIVY 219
            .:..|.||:.:......|:.|.|| |:|.::|.:|:|||     |.:....|             
plant   249 FDTTTNEWKLLTPVEEGPTPRSFH-SMAADEENVYVFGGVSATARLNTLDSY------------- 299

  Fly   220 LDMKTKVWHRPFTAGKVPVGRRSHSMFVYNKLIYVFGGYNGLLDQHFNDLYTFDPRTKLWNLIRA 284
             ::..|.|....|.|.....|....:.|....::|..|:||.   ..:|::.:||....|..:..
plant   300 -NIVDKKWFHCSTPGDSLTARGGAGLEVVQGKVWVVYGFNGC---EVDDVHYYDPVQDKWTQVET 360

  Fly   285 NGKAPTARRRQCAIVMGTRMFLFGGTSPRSGSSSSPAA-VSPTQETGGAAA 334
            .|..|:.|....:..:|..:.:|||.     .:..|.| |.|.|.|.|..|
plant   361 FGVRPSERSVFASAAIGKHIVIFGGE-----IAMDPLAHVGPGQLTDGTFA 406

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12081NP_001259343.1 KELCH repeat 13..69 CDD:276965 16/85 (19%)
Kelch_6 13..60 CDD:290672 14/76 (18%)
KELCH repeat 78..125 CDD:276965 16/48 (33%)
Kelch_1 78..117 CDD:279660 13/40 (33%)
KELCH repeat 128..170 CDD:276965 12/47 (26%)
Kelch_3 137..188 CDD:290151 15/50 (30%)
KELCH repeat 180..236 CDD:276965 16/60 (27%)
Kelch_3 192..248 CDD:290151 11/60 (18%)
Kelch_5 237..276 CDD:290565 9/38 (24%)
NSP1NP_001030709.1 PLN02193 1..470 CDD:177844 89/376 (24%)
Jacalin 13..142 CDD:279727 14/70 (20%)
KELCH repeat 166..211 CDD:276965 14/44 (32%)
Kelch_6 166..206 CDD:290672 12/39 (31%)
KELCH repeat 221..265 CDD:276965 10/45 (22%)
Kelch_3 228..277 CDD:290151 16/51 (31%)
Kelch_1 268..306 CDD:279660 13/52 (25%)
KELCH repeat 269..316 CDD:276965 16/61 (26%)
Kelch_1 318..358 CDD:279660 10/42 (24%)
KELCH repeat 319..358 CDD:276965 10/41 (24%)
KELCH repeat 368..417 CDD:276965 13/44 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 86 1.000 Inparanoid score I2331
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D933937at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
43.930

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