DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12081 and NSP3

DIOPT Version :9

Sequence 1:	NP_001259343.1	Gene:	CG12081 / 31799	FlyBaseID:	FBgn0030053	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001327031.1	Gene:	NSP3 / 820886	AraportID:	AT3G16390	Length:	467	Species:	Arabidopsis thaliana

Alignment Length:	330	Identity:	84/330 - (25%)
Similarity:	133/330 - (40%)	Gaps:	67/330 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 GGYCTGYDYRYNEPIDVHALNAHTM---------RWTLVPQQLDDAGVPLKYPLVPFQRYGHTVV 84
            ||...|:..|..:.:  |:|.|:..         .|..|.|..:..|:          |..|.:.
plant   120 GGKIVGFHGRSTDVL--HSLGAYVSLPSTPKLLGNWIKVEQNGEGPGL----------RCSHGIA 172

  Fly    85 AYKDRIYIWGGR--NDENLCNTLYCFDPKTAQWSRPQVTGCLPGARDGHSACV------IGNSMY 141
            ...::||.:||.  .::.:...||.||.:|..||....||.:|     |.:|:      :|:::|
plant   173 QVGNKIYSFGGELIPNQPIDKHLYVFDLETRTWSIAPATGDVP-----HLSCLGVRMVSVGSTLY 232

  Fly   142 IFGG--FVDEINEFSSDVHSLNLDTMEWRYVQTFGVPPSYRDFHASVAYEQERMYIFGGRG--DK 202
            .|||  |..:.|.|    :|.:..|.||:.:......|:.|.|| |:|.::|.:|:|||.|  |:
plant   233 TFGGRDFSRQYNGF----YSFDTTTNEWKLLTPVEEGPTPRSFH-SMAADEENVYVFGGVGAMDR 292

  Fly   203 HSPYHSQEETYCHEIVYLDMKTKVWHRPFTAGKVPVGRRSHSMFVYNKLIYVFGGYNGLLDQHFN 267
            .....|      :.||     .|.|......|.....|....:.|....:::..|:||.   ..:
plant   293 IKTLDS------YNIV-----DKTWFHCSNPGDSFSIRGGAGLEVVQGKVWIVYGFNGC---EVD 343

  Fly   268 DLYTFDPRTKLWNLIRANGKAPTARRRQCAIVMGTRMFLFGG---TSPRSGSSSSPAAVSPTQET 329
            |::.:||....|..:...|..|..|....:..:|..:.:|||   ..||       |.|.|.|..
plant   344 DVHFYDPAEDKWTQVETFGVKPNERSVFASAAIGKHIVIFGGEIAMDPR-------AHVGPGQLI 401

  Fly   330 GGAAA 334
            .|..|
plant   402 DGTFA 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12081	NP_001259343.1	KELCH repeat	13..69	CDD:276965	11/48 (23%)
		Kelch_6	13..60	CDD:290672	9/39 (23%)
		KELCH repeat	78..125	CDD:276965	15/48 (31%)
		Kelch_1	78..117	CDD:279660	12/40 (30%)
		KELCH repeat	128..170	CDD:276965	14/49 (29%)
		Kelch_3	137..188	CDD:290151	17/52 (33%)
		KELCH repeat	180..236	CDD:276965	18/57 (32%)
		Kelch_3	192..248	CDD:290151	13/57 (23%)
		Kelch_5	237..276	CDD:290565	8/38 (21%)
NSP3	NP_001327031.1	PLN02193	1..467	CDD:177844	84/330 (25%)
		KELCH repeat	166..211	CDD:276965	13/44 (30%)
		KELCH repeat	215..266	CDD:276965	15/59 (25%)
		KELCH repeat	269..311	CDD:276965	17/53 (32%)
		KELCH repeat	319..365	CDD:276965	10/48 (21%)
		KELCH repeat	368..417	CDD:276965	13/46 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	86	1.000	Inparanoid score	I2331
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.920