DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12081 and ACBP4

DIOPT Version :9

Sequence 1:	NP_001259343.1	Gene:	CG12081 / 31799	FlyBaseID:	FBgn0030053	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_974227.1	Gene:	ACBP4 / 819707	AraportID:	AT3G05420	Length:	669	Species:	Arabidopsis thaliana

Alignment Length:	418	Identity:	105/418 - (25%)
Similarity:	161/418 - (38%)	Gaps:	98/418 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 WTVHLDGGPQ---RVNHAAVGVGDFIYSFGGYCTGYDYRYNEPIDVHALNAHTMRWTLVPQQLDD 64
            ||.....|.:   |..|.|..:.|.:|.:||...|   ||..  |:|.|:..:..|:.|..::..
plant   172 WTAPQTSGQRPKARYEHGAAVIQDKMYIYGGNHNG---RYLG--DLHVLDLKSWTWSRVETKVAT 231

  Fly    65 AGVPLKYPLVPFQRYGHTVVAYKDRIYIWGGR-NDENLCNTLYCFDPKTAQWSRPQVTGCLPGAR 128
            .......|.:.....||:::|:.:::...||. .|.:....:..|||.|..||..:..|..|.:|
plant   232 ESQETSTPTLLAPCAGHSLIAWDNKLLSIGGHTKDPSESMQVKVFDPHTITWSMLKTYGKPPVSR 296

  Fly   129 DGHSACVIGNSMYIFGGFVDEINEFSSDVHSLNLDTMEWRYVQTFGVPPSYRDFHASVAYEQERM 193
            .|.|..::|.::.|||| .|......:|:|.|:||||.|..:...||.||.|..||:..:.:..:
plant   297 GGQSVTMVGKTLVIFGG-QDAKRSLLNDLHILDLDTMTWDEIDAVGVSPSPRSDHAAAVHAERFL 360

  Fly   194 YIFGGRGDKHSPYHSQEETYCHEIVYLDMKTKVWHRPFTAGKVPVGRRSHSMFVYNKLIYVFGGY 258
            .||||                                          .||:..
plant   361 LIFGG------------------------------------------GSHATC------------ 371

  Fly   259 NGLLDQHFNDLYTFDPRTKLWNLIRANGKAPTARRRQCAIVMGTRMFLFGGTSPRSGSSSSPAAV 323
                   |:||:..|.:|..|:.....|.|||.|.....:.:|...|:.||...:||:|.|....
plant   372 -------FDDLHVLDLQTMEWSRPAQQGDAPTPRAGHAGVTIGENWFIVGGGDNKSGASESVVLN 429

  Fly   324 SPTQETGGAAAAGGVVP---PGVALI--DYSDLHVLDFEPTLKTLATMVVL-----KHQLDISGL 378
            ..|......|:..|.||   .|::|:  .|:...||            |..     ::..:|:.|
plant   430 MSTLAWSVVASVQGRVPLASEGLSLVVSSYNGEDVL------------VAFGGYNGRYNNEINLL 482

  Fly   379 PRSFRSDLQMLT----QPNSISRPINQA 402
            ..|.:|.||..|    .|.|:| .:|.|
plant   483 KPSHKSTLQTKTLEAPLPGSLS-AVNNA 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12081	NP_001259343.1	KELCH repeat	13..69	CDD:276965	15/55 (27%)
		Kelch_6	13..60	CDD:290672	15/46 (33%)
		KELCH repeat	78..125	CDD:276965	13/47 (28%)
		Kelch_1	78..117	CDD:279660	11/39 (28%)
		KELCH repeat	128..170	CDD:276965	17/41 (41%)
		Kelch_3	137..188	CDD:290151	21/50 (42%)
		KELCH repeat	180..236	CDD:276965	7/55 (13%)
		Kelch_3	192..248	CDD:290151	6/55 (11%)
		Kelch_5	237..276	CDD:290565	6/38 (16%)
ACBP4	NP_974227.1	ACBP	14..99	CDD:279259
		PLN02153	171..416	CDD:177814	77/310 (25%)
		Kelch_1	184..225	CDD:279660	14/45 (31%)
		KELCH repeat	185..241	CDD:276965	16/60 (27%)
		Kelch_6	244..296	CDD:290672	14/51 (27%)
		KELCH repeat	245..293	CDD:276965	13/47 (28%)
		KELCH repeat	296..337	CDD:276965	17/41 (41%)
		Kelch_3	305..355	CDD:290151	21/50 (42%)
		KELCH repeat	347..395	CDD:276965	16/108 (15%)
		Kelch_3	357..406	CDD:290151	17/109 (16%)
		Kelch_5	395..432	CDD:290565	11/36 (31%)
		KELCH repeat	398..440	CDD:276965	10/41 (24%)
		Cortex-I_coil	552..639	CDD:286397
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	40	1.000	Domainoid score	I4832
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D933937at2759
OrthoFinder	1	1.000	-	-		FOG0001118
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.880