DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12081 and Klhdc8b

DIOPT Version :9

Sequence 1:NP_001259343.1 Gene:CG12081 / 31799 FlyBaseID:FBgn0030053 Length:403 Species:Drosophila melanogaster
Sequence 2:NP_001346357.1 Gene:Klhdc8b / 78267 MGIID:1925517 Length:354 Species:Mus musculus


Alignment Length:321 Identity:76/321 - (23%)
Similarity:110/321 - (34%) Gaps:76/321 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    71 YPLVPFQR-YGHTVVAYKD-RIYIWGGRNDENL-CNTLYCFDPKTAQWSRPQVTGCLPGARDGHS 132
            :|.:|..| ||  .||::| .:.:.||.....| .:|....|..:..|   .....||.||.|.:
Mouse    14 FPPMPTCRVYG--TVAHQDGHLLVLGGCGRAGLPLDTAETLDMGSHTW---LALAPLPTARAGAA 73

  Fly   133 ACVIGNSMYIFGGFVDEINEFSSDVHSLNLDTMEWRYVQT-----FGVPPSYRDFHASVAYEQER 192
            |.|:|..:.:.|| |||:....:.|.:...|...|....|     .||....||         ..
Mouse    74 AVVLGKQVLVVGG-VDEVQSPVAAVEAFLADEGRWERRATLPQAAMGVATVERD---------GM 128

  Fly   193 MYIFGGRGDKHSPYHSQEETYCHEIVYLDMKTKVWHRPFTAGKVPVGRRSHSMFVYNKLIYVFGG 257
            :|..||.|...:|.        .:::..:.:...|   .:...:|......|.|::...|||.||
Mouse   129 VYALGGMGPDTAPQ--------AQVLVYEPRRDCW---LSLPSMPTPCYGASTFLHGNKIYVLGG 182

  Fly   258 YNGLLDQHFNDLYTFDPRTKLWNLIRANGKAPTARRRQCAIVMGTRMFLFGGTSPRSGSSSSPAA 322
            ..|.|.  ......||..|:.|.      :.|:...|:.          |.|.:...||..|   
Mouse   183 RQGKLP--VTAFEAFDLETRTWT------RHPSLPSRRA----------FAGCAMAEGSVFS--- 226

  Fly   323 VSPTQETGGAAAAGGVVPPGVALIDYSDLHVLDFEPTLKTLATMVVLKHQLDISGLPRSFR 383
                        .||:..||.        |.....|.......|..|:|. ..:.||||.|
Mouse   227 ------------LGGLQQPGP--------HNFYSRPHFVNTVEMFDLEHG-SWTKLPRSLR 266

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12081NP_001259343.1 KELCH repeat 13..69 CDD:276965
Kelch_6 13..60 CDD:290672
KELCH repeat 78..125 CDD:276965 12/49 (24%)
Kelch_1 78..117 CDD:279660 12/41 (29%)
KELCH repeat 128..170 CDD:276965 13/41 (32%)
Kelch_3 137..188 CDD:290151 14/55 (25%)
KELCH repeat 180..236 CDD:276965 8/55 (15%)
Kelch_3 192..248 CDD:290151 9/55 (16%)
Kelch_5 237..276 CDD:290565 12/38 (32%)
Klhdc8bNP_001346357.1 Kelch 1 1..31 7/18 (39%)
PHA03098 <7..210 CDD:222983 56/229 (24%)
KELCH repeat 21..66 CDD:276965 12/49 (24%)
Kelch 2 32..79 13/49 (27%)
KELCH repeat 69..113 CDD:276965 13/44 (30%)
Kelch 3 81..127 13/55 (24%)
KELCH repeat 117..162 CDD:276965 10/64 (16%)
Kelch 4 128..175 9/57 (16%)
PHA03098 <129..336 CDD:222983 41/191 (21%)
KELCH repeat 165..210 CDD:276965 14/52 (27%)
Kelch 5 176..222 15/63 (24%)
KELCH repeat 212..262 CDD:276965 14/83 (17%)
Kelch 6 224..281 15/67 (22%)
KELCH repeat 271..317 CDD:276965
Kelch 7 282..329
Kelch 8 331..354
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D933937at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.920

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