DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG12081 and Lztr1

DIOPT Version :9

Sequence 1:NP_001259343.1 Gene:CG12081 / 31799 FlyBaseID:FBgn0030053 Length:403 Species:Drosophila melanogaster
Sequence 2:NP_080084.2 Gene:Lztr1 / 66863 MGIID:1914113 Length:837 Species:Mus musculus


Alignment Length:362 Identity:93/362 - (25%)
Similarity:149/362 - (41%) Gaps:72/362 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 GGPQRVNHAAVGVGDFIYSFGGY------CTGYDYRYNEPIDVHALN------AHTMRWTLVPQQ 61
            |||       :|.|...   ||.      ...:|:..::.::...||      .|  ||..:|..
Mouse     5 GGP-------IGSGALT---GGVRSKVAPSVDFDHSCSDSVEYLTLNFGPFETVH--RWRRLPPC 57

  Fly    62 LDDAGVPLKYPLVPFQRYGHTVVAYKDRIYIWGGRNDENLCNTLYCFDPKTAQWSRPQVTGCLPG 126
            .:..|.         :|..||||||||.||::||.|.:.:.|.|..||.|...|.|...||..|.
Mouse    58 DEFVGA---------RRSKHTVVAYKDAIYVFGGDNGKTMLNDLLRFDVKDCSWCRAFTTGTPPA 113

  Fly   127 ARDGHSACVIGNSMYIFGGFVDEINEFS-----SDVHSLNLDTMEWRYVQTFGVPPSYRDFHASV 186
            .|..|||.|.|:||::|||:..:|...|     :|:......|.:|...:..|..|..|..|.:.
Mouse   114 PRYHHSAVVYGSSMFVFGGYTGDIYSNSNLKNKNDLFEYKFATGQWTEWKIEGRLPVARSAHGAT 178

  Fly   187 AYEQERMYIFGGRGDKHSPYHSQEETYCHEIVYLDMKTKVWHRPFTAGKVPVGRRSHSMFVYNKL 251
            .| .::::||.|. |.::..:..     ..|...|.:...|.....:|::|....:..:.|....
Mouse   179 VY-SDKLWIFAGY-DGNARLNDM-----WTIGLQDRELTCWEEVAQSGEIPPSCCNFPVAVCRDK 236

  Fly   252 IYVFGGYNGLLDQHFNDLYTFDPRTKLW------NLIRANGKAPTARRRQCAIVMGTRMFLFGGT 310
            ::||.|.:|.  :..|:|:.|:.:.|.|      :|:|.:...|..|.....:.....:::||| 
Mouse   237 MFVFSGQSGA--KITNNLFQFEFKDKTWTRIPTEHLLRGSPPPPQRRYGHTMVAFDRHLYVFGG- 298

  Fly   311 SPRSGSSSSP-------------AAVSPT--QETGGA 332
               :..::.|             ..|.|:  .|.|||
Mouse   299 ---AADNTLPNELHCYDVDFQTWEVVQPSSDSEVGGA 332

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12081NP_001259343.1 KELCH repeat 13..69 CDD:276965 12/67 (18%)
Kelch_6 13..60 CDD:290672 10/58 (17%)
KELCH repeat 78..125 CDD:276965 23/46 (50%)
Kelch_1 78..117 CDD:279660 20/38 (53%)
KELCH repeat 128..170 CDD:276965 16/46 (35%)
Kelch_3 137..188 CDD:290151 15/55 (27%)
KELCH repeat 180..236 CDD:276965 11/55 (20%)
Kelch_3 192..248 CDD:290151 9/55 (16%)
Kelch_5 237..276 CDD:290565 9/38 (24%)
Lztr1NP_080084.2 KELCH repeat 65..111 CDD:276965 23/45 (51%)
Kelch_3 74..123 CDD:290151 21/48 (44%)
Kelch 1. /evidence=ECO:0000255 76..125 20/48 (42%)
KELCH repeat 115..169 CDD:276965 17/53 (32%)
Kelch_3 124..180 CDD:290151 15/55 (27%)
Kelch 2. /evidence=ECO:0000255 127..182 14/55 (25%)
Kelch_4 171..217 CDD:290154 10/52 (19%)
Kelch 3. /evidence=ECO:0000255 184..235 10/56 (18%)
Kelch_3 234..289 CDD:290151 13/56 (23%)
Kelch 4. /evidence=ECO:0000255 236..282 12/47 (26%)
Kelch_1 280..323 CDD:279660 6/46 (13%)
KELCH repeat 281..323 CDD:276965 6/45 (13%)
Kelch 5. /evidence=ECO:0000255 292..338 10/45 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 324..352 4/9 (44%)
Kelch 6. /evidence=ECO:0000255 396..447
SPOP_C_like 571..631 CDD:269810
BTB 662..761 CDD:279045
BTB 665..762 CDD:197585
SPOP_C_like 765..>804 CDD:269810
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1494
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.940

Return to query results.
Submit another query.