DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12081 and hcfc1a

DIOPT Version :9

Sequence 1:NP_001259343.1 Gene:CG12081 / 31799 FlyBaseID:FBgn0030053 Length:403 Species:Drosophila melanogaster
Sequence 2:XP_005169361.1 Gene:hcfc1a / 564853 ZFINID:ZDB-GENE-030912-10 Length:1802 Species:Danio rerio


Alignment Length:253 Identity:73/253 - (28%)
Similarity:120/253 - (47%) Gaps:20/253 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly    74 VPFQRYGHTVVAYKDRIYIWGGRNDENLCNTLYCFDPKTAQWSRPQVTGCLPGARDGHSACVIGN 138
            ||..|:||..||.|:.:.::||.| |.:.:.|:.::..|.||..|.|.|.:|.....:.....|.
Zfish    28 VPRPRHGHRAVAIKELMVVFGGGN-EGIVDELHVYNTATNQWFIPAVRGDIPPGCAAYGFVCDGT 91

  Fly   139 SMYIFGGFVDEINEFSSDVHSLNLDTMEWRYVQ----TFGVPPSYRDFHASVAYEQERMYIFGGR 199
            .:.:|||.| |..::|:|::.|.....||:.::    ..||||..|..| |.:....:.|:|||.
Zfish    92 RLLVFGGMV-EYGKYSNDLYELQASRWEWKKLKPKAPKNGVPPCPRLGH-SFSLVGNKCYLFGGL 154

  Fly   200 GDKHSPYHSQEETYCHEIVYLDMK----TKVWHRPFTAGKVPVGRRSHSMFVYNKLI------YV 254
            .:......:....|.:::..|:::    ...|..|.|.|.:|..|.||:..:|.:.:      .:
Zfish   155 ANDSEDPKNNIPRYLNDLYTLELRPGSSVAGWDVPVTYGVLPPPRESHTAVIYTEKVTKKSRLVI 219

  Fly   255 FGGYNGLLDQHFNDLYTFDPRTKLWNLIRANGKAPTARRRQCAIVMGTRMFLFGGTSP 312
            :||.:|.   ...||:|.|..|..||....:|.||..|....|..:..:|::|||..|
Zfish   220 YGGMSGC---RLGDLWTLDIDTLTWNKPAISGAAPLPRSLHSATTITNKMYVFGGWVP 274

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12081NP_001259343.1 KELCH repeat 13..69 CDD:276965
Kelch_6 13..60 CDD:290672
KELCH repeat 78..125 CDD:276965 17/46 (37%)
Kelch_1 78..117 CDD:279660 14/38 (37%)
KELCH repeat 128..170 CDD:276965 11/41 (27%)
Kelch_3 137..188 CDD:290151 18/54 (33%)
KELCH repeat 180..236 CDD:276965 13/59 (22%)
Kelch_3 192..248 CDD:290151 14/59 (24%)
Kelch_5 237..276 CDD:290565 12/44 (27%)
hcfc1aXP_005169361.1 PLN02153 12..332 CDD:177814 73/253 (29%)
Kelch_1 31..68 CDD:279660 12/37 (32%)
KELCH repeat 32..79 CDD:276965 17/47 (36%)
KELCH repeat 83..133 CDD:276965 13/50 (26%)
Kelch_3 90..144 CDD:290151 18/55 (33%)
KELCH repeat 199..252 CDD:276965 16/55 (29%)
Kelch_3 214..262 CDD:290151 15/50 (30%)
KELCH repeat 254..318 CDD:276965 7/21 (33%)
Kelch_3 263..329 CDD:290151 5/12 (42%)
Kelch_5 318..>350 CDD:290565
FN3 <1624..1653 CDD:238020
FN3 1659..1763 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1494
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.940

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