Protein Alignment CG12081 and Hcf

DIOPT Version :10

• Sequence 1: NP_572494.1
• Gene: CG12081 / 31799
• FlyBaseID: FBgn0030053
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_524621.2
• Gene: Hcf / 43788
• FlyBaseID: FBgn0039904
• Length: 1500
• Species: Drosophila melanogaster
• Alignment Length: 417
• Identity: 96/417 - (23%)
• Similarity: 170/417 - (40%)
• Gaps: 77/417 - (18%)

  Fly    44 DVHALNAHT--MRWTLVPQQLDDAGVPLKYPLVPFQRYGHTVVAYKDRIYIWGGRNDENLCNTLY 106
            |.|.|:::.  .||..|   |:..|..      |..|:||..:..|:.:.::||.| |.:.:.|:
  Fly    47 DGHQLDSNLTGFRWKRV---LNPTGPQ------PRPRHGHRAINIKELMVVFGGGN-EGIVDELH 101

  Fly   107 CFDPKTAQWSRPQVTGCLPGARDGHSACVIGNSMYIFGGFVDEINEFSSDVHSLNLDTMEWR--Y 169
            .::..|.||..|.:.|.:|.....:...|.|..|::|||.: |..::|::::.|.....|||  |
  Fly   102 VYNTVTNQWYVPVLKGDVPNGCAAYGFVVEGTRMFVFGGMI-EYGKYSNELYELQATKWEWRKMY 165

  Fly   170 VQT--FGVPPSYRDFHASVAYEQERMYIFGGRGDKHSPYHSQEETYCHEIVYLDMK-----TKVW 227
            .::  .|:.|..|..| |.....|::::|||..::.....:....|.:::..||.:     ...|
  Fly   166 PESPDSGLSPCPRLGH-SFTMVGEKIFLFGGLANESDDPKNNIPKYLNDLYILDTRGVHSHNGKW 229

  Fly   228 HRPFTAGKVPVGRRSHSMFVY------NKLIYVFGGYNGLLDQHFNDLYTFDPRTKLWNLIRANG 286
            ..|.|.|..|..|.||:...:      |..:.::||.:|.   ...||:..:..:..|:..:.:|
  Fly   230 IVPKTYGDSPPPRESHTGISFATKSNGNLNLLIYGGMSGC---RLGDLWLLETDSMTWSKPKTSG 291

  Fly   287 KAPTARRRQCAIVMGTRMFLFGG-----------TSPRSGSSSSPAAV------------SPTQE 328
            :||..|....:.::|.:|::|||           |:.|....::..||            ..|.|
  Fly   292 EAPLPRSLHSSTMIGNKMYVFGGWVPLVINDSKSTTEREWKCTNTLAVLDLETMTWENVTLDTVE 356

  Fly   329 TGGAAAAGGVVPPGVALIDY------------------SDLHVLDFEPTLKTLATMVV--LKHQL 373
            .....|..|....|:....|                  .||..|:....|..:...:|  ..|.|
  Fly   357 ENVPRARAGHCAVGIQSRLYVWSGRDGYRKAWNNQVCCKDLWYLEVSKPLYAVKVALVRASTHAL 421

  Fly   374 DISGLPRSFRSDLQMLTQPNSISRPIN 400
            ::|....:|.:  ..:.|...|.:|:|
  Fly   422 ELSWTATTFAA--AYVLQIQKIEQPLN 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12081	NP_572494.1	NanM	13..306	CDD:442289	70/278 (25%)
		KELCH repeat	13..69	CDD:276965	8/26 (31%)
		KELCH repeat	78..125	CDD:276965	14/46 (30%)
		KELCH repeat	128..170	CDD:276965	12/43 (28%)
		KELCH repeat	180..236	CDD:276965	14/60 (23%)
Hcf	NP_524621.2	PLN02193	<59..363	CDD:177844	76/318 (24%)
		KELCH repeat	74..115	CDD:276965	13/41 (32%)
		KELCH repeat	123..175	CDD:276965	14/52 (27%)
		KELCH repeat	178..239	CDD:276965	14/61 (23%)
		KELCH repeat	297..360	CDD:276965	12/62 (19%)
		FN3	<1307..>1381	CDD:442628
		FN3	<1307..1338	CDD:238020
		FN3	1344..1448	CDD:238020