DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12081 and Hcf

DIOPT Version :9

Sequence 1:NP_001259343.1 Gene:CG12081 / 31799 FlyBaseID:FBgn0030053 Length:403 Species:Drosophila melanogaster
Sequence 2:NP_524621.2 Gene:Hcf / 43788 FlyBaseID:FBgn0039904 Length:1500 Species:Drosophila melanogaster


Alignment Length:417 Identity:96/417 - (23%)
Similarity:170/417 - (40%) Gaps:77/417 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    44 DVHALNAHT--MRWTLVPQQLDDAGVPLKYPLVPFQRYGHTVVAYKDRIYIWGGRNDENLCNTLY 106
            |.|.|:::.  .||..|   |:..|..      |..|:||..:..|:.:.::||.| |.:.:.|:
  Fly    47 DGHQLDSNLTGFRWKRV---LNPTGPQ------PRPRHGHRAINIKELMVVFGGGN-EGIVDELH 101

  Fly   107 CFDPKTAQWSRPQVTGCLPGARDGHSACVIGNSMYIFGGFVDEINEFSSDVHSLNLDTMEWR--Y 169
            .::..|.||..|.:.|.:|.....:...|.|..|::|||.: |..::|::::.|.....|||  |
  Fly   102 VYNTVTNQWYVPVLKGDVPNGCAAYGFVVEGTRMFVFGGMI-EYGKYSNELYELQATKWEWRKMY 165

  Fly   170 VQT--FGVPPSYRDFHASVAYEQERMYIFGGRGDKHSPYHSQEETYCHEIVYLDMK-----TKVW 227
            .::  .|:.|..|..| |.....|::::|||..::.....:....|.:::..||.:     ...|
  Fly   166 PESPDSGLSPCPRLGH-SFTMVGEKIFLFGGLANESDDPKNNIPKYLNDLYILDTRGVHSHNGKW 229

  Fly   228 HRPFTAGKVPVGRRSHSMFVY------NKLIYVFGGYNGLLDQHFNDLYTFDPRTKLWNLIRANG 286
            ..|.|.|..|..|.||:...:      |..:.::||.:|.   ...||:..:..:..|:..:.:|
  Fly   230 IVPKTYGDSPPPRESHTGISFATKSNGNLNLLIYGGMSGC---RLGDLWLLETDSMTWSKPKTSG 291

  Fly   287 KAPTARRRQCAIVMGTRMFLFGG-----------TSPRSGSSSSPAAV------------SPTQE 328
            :||..|....:.::|.:|::|||           |:.|....::..||            ..|.|
  Fly   292 EAPLPRSLHSSTMIGNKMYVFGGWVPLVINDSKSTTEREWKCTNTLAVLDLETMTWENVTLDTVE 356

  Fly   329 TGGAAAAGGVVPPGVALIDY------------------SDLHVLDFEPTLKTLATMVV--LKHQL 373
            .....|..|....|:....|                  .||..|:....|..:...:|  ..|.|
  Fly   357 ENVPRARAGHCAVGIQSRLYVWSGRDGYRKAWNNQVCCKDLWYLEVSKPLYAVKVALVRASTHAL 421

  Fly   374 DISGLPRSFRSDLQMLTQPNSISRPIN 400
            ::|....:|.:  ..:.|...|.:|:|
  Fly   422 ELSWTATTFAA--AYVLQIQKIEQPLN 446

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12081NP_001259343.1 KELCH repeat 13..69 CDD:276965 8/26 (31%)
Kelch_6 13..60 CDD:290672 6/17 (35%)
KELCH repeat 78..125 CDD:276965 14/46 (30%)
Kelch_1 78..117 CDD:279660 12/38 (32%)
KELCH repeat 128..170 CDD:276965 12/43 (28%)
Kelch_3 137..188 CDD:290151 17/54 (31%)
KELCH repeat 180..236 CDD:276965 14/60 (23%)
Kelch_3 192..248 CDD:290151 14/60 (23%)
Kelch_5 237..276 CDD:290565 10/44 (23%)
HcfNP_524621.2 Kelch_1 73..110 CDD:279660 10/37 (27%)
KELCH repeat 74..115 CDD:276965 13/41 (32%)
KELCH repeat 123..175 CDD:276965 14/52 (27%)
Kelch_3 132..184 CDD:290151 17/53 (32%)
Kelch_5 175..221 CDD:290565 11/46 (24%)
KELCH repeat 178..239 CDD:276965 14/61 (23%)
Kelch_3 260..305 CDD:290151 10/47 (21%)
KELCH repeat 297..360 CDD:276965 12/62 (19%)
Kelch_3 306..371 CDD:290151 13/64 (20%)
FN3 <1307..1338 CDD:238020
FN3 1344..1448 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45446734
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - mtm9219
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1494
SonicParanoid 00.000 Not matched by this tool.
43.870

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