Protein Alignment CG12081 and Klhdc3

DIOPT Version :10

• Sequence 1: NP_572494.1
• Gene: CG12081 / 31799
• FlyBaseID: FBgn0030053
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: XP_038939750.1
• Gene: Klhdc3 / 363192
• RGDID: 1307105
• Length: 398
• Species: Rattus norvegicus
• Alignment Length: 417
• Identity: 192/417 - (46%)
• Similarity: 249/417 - (59%)
• Gaps: 53/417 - (12%)

  Fly     3 WTVHLDGGPQRVNHAAVGVGDFIYSFGGYCTGYDYRYNEPIDVHALNAHTMRWTLVPQQLDDAGV 67
            |||||:|||:|||||||.||..:|||||||:|.||.....||||..||.::|||.:|
  Rat     4 WTVHLEGGPRRVNHAAVAVGHRVYSFGGYCSGEDYETLRQIDVHIFNAVSLRWTKLP-------- 60

  Fly    68 PLK------YPLVPFQRYGHTVVAYKDRIYIWGGRND-ENLCNTLYCFDPKTAQWSRPQVTGCLP 125
            |::      .|:||:.||||:.|...|.:::|||||| |..||.||.||..|.:||.|:|:|.:|
  Rat    61 PVRPAVRGQAPVVPYMRYGHSTVLIDDTVFLWGGRNDTEGACNVLYAFDVNTHKWSTPRVSGTVP 125

  Fly   126 GARDGHSACVIGNSMYIFGGFVDEINEFSSDVHSLNLDTMEWRYVQTFGVPPSYRDFHASVAYEQ 190
            ||||||||||:|..||||||:....:.||:|:|.|:..||.|..|.|.|.|..:|||| |.....
  Rat   126 GARDGHSACVLGKIMYIFGGYEQLADCFSNDIHKLDTSTMTWTLVCTKGNPARWRDFH-SATMLG 189

  Fly   191 ERMYIFGGRGDKHSPYHSQEETYCHEIVYLDMKTKVW----HRPFTAGKVPVGRRSHSMFVYNKL 251
            ..||:||||.|:..|:||..|.||:.|...|.:|:.|    |.|.    :|.||||||.|.||..
  Rat   190 NHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEAWLDCPHTPV----LPEGRRSHSAFGYNGE 250

  Fly   252 IYVFGGYNGLLDQHFNDLYTFDPRTKLWNLIRANGKAPTARRRQCAIVMGTRMFLFGGTSPRSGS 316
            :|:|||||..|::||:||:.|:|.:..|..|...||.|..|||||..::|.::.|||||||
  Rat   251 LYIFGGYNARLNRHFHDLWKFNPGSFTWKKIEPKGKGPCPRRRQCCCIVGDKIVLFGGTSP---- 311

  Fly   317 SSSPAAVSPTQETGGAAAAGGVVPPGVALIDYSDLHVLDFEPTLKTLATMVVLKHQLDISGLPRS 381
                   ||.:..|..          ..|||:||||:|||.|:||||..:.|:::.||.|.||..
  Rat   312 -------SPEEGLGDE----------FDLIDHSDLHILDFSPSLKTLCKLAVIQYNLDQSCLPHD 359

  Fly   382 FRSDLQMLTQP------NSISRPINQA 402
            .|.  :.|..|      :|:..||:.|
  Rat   360 IRE--KSLLPPLLSLLLSSLPLPISPA 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12081	NP_572494.1	NanM	13..306	CDD:442289	146/303 (48%)
		KELCH repeat	13..69	CDD:276965	29/55 (53%)
		KELCH repeat	78..125	CDD:276965	25/47 (53%)
		KELCH repeat	128..170	CDD:276965	23/41 (56%)
		KELCH repeat	180..236	CDD:276965	24/59 (41%)
Klhdc3	XP_038939750.1	NanM	14..308	CDD:442289	148/306 (48%)
		KELCH repeat	14..62	CDD:276965	29/55 (53%)
		KELCH repeat	77..124	CDD:276965	25/46 (54%)
		KELCH repeat	128..173	CDD:276965	24/44 (55%)
		KELCH repeat	180..236	CDD:276965	24/60 (40%)
		KELCH repeat	239..283	CDD:276965	23/43 (53%)