Protein Alignment CG12081 and Klhdc4

DIOPT Version :10

• Sequence 1: NP_572494.1
• Gene: CG12081 / 31799
• FlyBaseID: FBgn0030053
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_001414476.1
• Gene: Klhdc4 / 307917
• RGDID: 1561676
• Length: 589
• Species: Rattus norvegicus
• Alignment Length: 415
• Identity: 100/415 - (24%)
• Similarity: 148/415 - (35%)
• Gaps: 111/415 - (26%)

  Fly    23 DFIYSFGG-YCTGY-DYRYNEPIDVHALNAHTMRWTLVPQQLDDAGVPLKYPLVPFQRYGHTVVA 85
            |.:..||| |..|. .:.||| :.::::...|  ||.|           ..|..|.:|..|..|.
  Rat    76 DELILFGGEYFNGQKTFMYNE-LYIYSIRKGT--WTKV-----------DIPGPPPRRCAHQAVV 126

  Fly    86 YKD---RIYIWGGR----NDENLCN--TLYCFDPKTAQWSRPQVTGCLPGARDGHSACVIGNSMY 141
            ...   :::|:||.    :.|...:  .|:.....|..|.:.:.||. |..|.||........:.
  Rat   127 VPQGGGQLWIFGGEFASPDGEQFYHYKDLWVLHLATKTWEQIRSTGG-PSGRSGHRMVAWKRQLI 190

  Fly   142 IFGGFVDEINE--FSSDVHSLNLDTMEWRYVQTFGVPPSYRDFHASVAYEQERMYIFGG------ 198
            :||||.:...:  :.|||::.:|||..|..:...|..|:.|.........|..:.|:||
  Rat   191 LFGGFHESTRDYIYYSDVYTFSLDTFLWSKLSPSGPGPTPRSGCLMAVTPQGSIAIYGGYSKQRV 255

  Fly   199 -----RGDKHS------PYHSQEETYCHEIVYLDMKTKVWHRPFTAGKVPVGRRSHSMFVY-NKL 251
                 :|.:||      |....|:.:            .|.|...:|..|..|...|:.|. |..
  Rat   256 KKDVDKGTQHSDMFLLKPEDGGEDKW------------TWTRVNPSGVKPTVRSGFSVAVAPNHQ 308

  Fly   252 IYVFGGY------NGLLDQHFNDLYTFDPRTKLWNLIRANGKAPTARRRQCAIVMGTRMFLFGGT 310
            |.||||.      ..|....|||||.:|.....|...:..|.....:||
  Rat   309 ILVFGGVCDEEEEEHLEGSFFNDLYIYDAAKSRWFAAQLKGPKSEKKRR---------------- 357

  Fly   311 SPRSGSSSSPAAVSPTQETGGAAA--------------------------AG-GVVPPGVALIDY 348
              |.|.:..|...: .:||||.:|                          :| ||.||..|....
  Rat   358 --RRGKADDPEGAT-EEETGGTSAPEPLEVIKEVVSEDGTVITIKQVLTPSGLGVQPPPKADDSA 419

  Fly   349 SDLHVLDFEPTLKTLATMVVLKHQL 373
            |:......||..::.| |:.:||.|
  Rat   420 SEASSTGQEPCPRSSA-MLAVKHGL 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12081	NP_572494.1	NanM	13..306	CDD:442289	78/319 (24%)
		KELCH repeat	13..69	CDD:276965	13/47 (28%)
		KELCH repeat	78..125	CDD:276965	12/55 (22%)
		KELCH repeat	128..170	CDD:276965	14/43 (33%)
		KELCH repeat	180..236	CDD:276965	13/72 (18%)
Klhdc4	NP_001414476.1	None