DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12081 and Rabepk

DIOPT Version :9

Sequence 1:NP_001259343.1 Gene:CG12081 / 31799 FlyBaseID:FBgn0030053 Length:403 Species:Drosophila melanogaster
Sequence 2:NP_663497.2 Gene:Rabepk / 227746 MGIID:2139530 Length:380 Species:Mus musculus


Alignment Length:356 Identity:94/356 - (26%)
Similarity:145/356 - (40%) Gaps:79/356 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 RVNHAA---VGVGDF----IYSFGGYCTGYDYRYNEPIDVHALNAHTMRWTLVPQQLDDAGVPLK 70
            ||.|:.   ..|||.    |:..||......:.     |||.::..|.:|....::         
Mouse    39 RVGHSCSYFPPVGDAESGKIFIVGGANPNQSFS-----DVHTMDLGTHQWDTATRE--------- 89

  Fly    71 YPLVPFQRYGHTVV---AYKDRIYIWGGRNDENLCNTLYCFDPKTAQWSRPQVTGCLPGARDGH- 131
             .|:|  ||.|...   .....|:::||.:.....|.|....|:...||.|:|||..|..|..| 
Mouse    90 -GLLP--RYEHASFLPSCSPHSIWVFGGADQSGNRNCLQVMSPEDRTWSTPEVTGSPPSPRTFHT 151

  Fly   132 SACVIGNSMYIFGGF------VDEINEFSSDVHSLNLDTMEWRYVQTFGVPPSYRDFHASVAYEQ 190
            |:..|||.:|:|||.      |:::.     :|..:.:|:.|...:|.|.|||.|..|..|| ..
Mouse   152 SSAAIGNQLYVFGGGERGAQPVEDVK-----LHVFDANTLTWSQPETHGSPPSPRHGHVMVA-AG 210

  Fly   191 ERMYIFGG-RGDKHSPYHSQEETYCHEIVYLDMKTKVWHRPFTAGKVPVGRRSHSMFVYNKLIYV 254
            .:::|.|| .|||..     ::.:|     :|:....|.:....|.||||..:|:.......:|:
Mouse   211 TKLFIHGGLAGDKFF-----DDLHC-----IDIGDMSWQKLGPTGAVPVGCAAHAAVAVGHHVYM 265

  Fly   255 FGGY--NGLLDQHFNDLYTFDPRTKLWNLIRANGKAPTAR--RRQCAI---VMGTRMFLFGGTSP 312
            |||.  .|.|    |.:|.:....:.|.:::.:...|..|  ...|.|   ||.|          
Mouse   266 FGGMTATGAL----NMMYKYHTEKQHWTVLQFDTSLPAGRLDHSMCVIPWPVMST---------- 316

  Fly   313 RSGSSSSPAAVSPTQETGGAAA------AGG 337
             |.:..|.:.:...|:..|.||      :||
Mouse   317 -SENKDSDSVILTLQDEKGDAAEKAETQSGG 346

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12081NP_001259343.1 KELCH repeat 13..69 CDD:276965 14/62 (23%)
Kelch_6 13..60 CDD:290672 14/53 (26%)
KELCH repeat 78..125 CDD:276965 15/49 (31%)
Kelch_1 78..117 CDD:279660 10/41 (24%)
KELCH repeat 128..170 CDD:276965 14/48 (29%)
Kelch_3 137..188 CDD:290151 18/56 (32%)
KELCH repeat 180..236 CDD:276965 14/56 (25%)
Kelch_3 192..248 CDD:290151 15/56 (27%)
Kelch_5 237..276 CDD:290565 12/40 (30%)
RabepkNP_663497.2 Kelch_2 38..90 CDD:369447 14/65 (22%)
Kelch 1 57..103 13/62 (21%)
KELCH repeat 94..143 CDD:276965 15/48 (31%)
Kelch_3 107..155 CDD:379174 16/47 (34%)
Kelch 2 108..154 16/45 (36%)
PLN02193 <134..>302 CDD:177844 55/187 (29%)
KELCH repeat 147..198 CDD:276965 16/55 (29%)
Kelch 3 159..211 17/57 (30%)
KELCH repeat 201..243 CDD:276965 13/52 (25%)
Kelch 4 212..258 15/55 (27%)
KELCH repeat 251..291 CDD:276965 10/43 (23%)
Kelch 5 262..311 13/52 (25%)
Kelch 6 357..380
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D933937at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1494
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.950

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