DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12081 and Hcfc1

DIOPT Version :9

Sequence 1:NP_001259343.1 Gene:CG12081 / 31799 FlyBaseID:FBgn0030053 Length:403 Species:Drosophila melanogaster
Sequence 2:XP_006527898.1 Gene:Hcfc1 / 15161 MGIID:105942 Length:2090 Species:Mus musculus


Alignment Length:254 Identity:77/254 - (30%)
Similarity:122/254 - (48%) Gaps:22/254 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    74 VPFQRYGHTVVAYKDRIYIWGGRNDENLCNTLYCFDPKTAQWSRPQVTGCLPGARDGHSACVIGN 138
            ||..|:||..||.|:.|.::||.| |.:.:.|:.::..|.||..|.|.|.:|.....:.....|.
Mouse    29 VPRPRHGHRAVAIKELIVVFGGGN-EGIVDELHVYNTATNQWFIPAVRGDIPPGCAAYGFVCDGT 92

  Fly   139 SMYIFGGFVDEINEFSSDVHSLNLDTMEWRYVQT----FGVPPSYRDFHASVAYEQERMYIFGGR 199
            .:.:|||.| |..::|:|::.|.....||:.::.    .|.||..|..| |.:....:.|:|||.
Mouse    93 RLLVFGGMV-EYGKYSNDLYELQASRWEWKRLKAKTPKNGPPPCPRLGH-SFSLVGNKCYLFGGL 155

  Fly   200 GDKHSPYHSQEETYCHEIVYLDMK----TKVWHRPFTAGKVPVGRRSHSMFVY-------NKLIY 253
            .:......:....|.:::..|:::    ...|..|.|.|.:|..|.||:..||       :||: 
Mouse   156 ANDSEDPKNNIPRYLNDLYILELRPGSGVVAWDIPITYGVLPPPRESHTAVVYTEKDNKKSKLV- 219

  Fly   254 VFGGYNGLLDQHFNDLYTFDPRTKLWNLIRANGKAPTARRRQCAIVMGTRMFLFGGTSP 312
            ::||.:|.   ...||:|.|..|..||....:|.||..|....|..:|.:|::|||..|
Mouse   220 IYGGMSGC---RLGDLWTLDIETLTWNKPSLSGVAPLPRSLHSATTIGNKMYVFGGWVP 275

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12081NP_001259343.1 KELCH repeat 13..69 CDD:276965
Kelch_6 13..60 CDD:290672
KELCH repeat 78..125 CDD:276965 18/46 (39%)
Kelch_1 78..117 CDD:279660 15/38 (39%)
KELCH repeat 128..170 CDD:276965 11/41 (27%)
Kelch_3 137..188 CDD:290151 17/54 (31%)
KELCH repeat 180..236 CDD:276965 13/59 (22%)
Kelch_3 192..248 CDD:290151 14/59 (24%)
Kelch_5 237..276 CDD:290565 15/45 (33%)
Hcfc1XP_006527898.1 PLN02193 <27..322 CDD:177844 77/254 (30%)
KELCH repeat 33..80 CDD:276965 18/47 (38%)
KELCH repeat 84..134 CDD:276965 12/50 (24%)
KELCH repeat 137..196 CDD:276965 13/59 (22%)
KELCH repeat 200..253 CDD:276965 19/56 (34%)
KELCH repeat 255..319 CDD:276965 8/21 (38%)
Kelch_5 319..>351 CDD:372758
KELCH repeat 322..367 CDD:276965
Herpes_BLLF1 <441..771 CDD:282904
FN3 <1911..1940 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1494
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.940

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