DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12081 and klhdc1

DIOPT Version :9

Sequence 1:	NP_001259343.1	Gene:	CG12081 / 31799	FlyBaseID:	FBgn0030053	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	XP_021336373.1	Gene:	klhdc1 / 101883226	-ID:	-	Length:	230	Species:	Danio rerio

Alignment Length:	216	Identity:	54/216 - (25%)
Similarity:	87/216 - (40%)	Gaps:	49/216 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 QRYGHTVVAYKDRIYIWGG----RNDENLC--NTLYCFDPKTAQWSRPQVTGCLPGARDGHSACV 135
            :|.||...|.:..:|||||    .:.|...  :.::.:|.:...|...||.|..|....|.|:|:
Zfish    36 ERSGHAAAADRQHLYIWGGYASVADQEQFLPRDEIWIYDLERGSWCVRQVCGSAPPPLSGSSSCL 100

  Fly   136 IGNSMYIFGGFVDEINEFSSDVHSLNLDTMEW---RYVQTFGVPPSYRDFHASVAYEQERMYIFG 197
            :...::||||..|:..  :::::|::|....:   |.....|.|||.||......:| .|:..||
Zfish   101 LDGELFIFGGCSDDGQ--TNELYSISLGDGRFTCRRVTHRSGSPPSPRDKLCCWLHE-GRIVFFG 162

  Fly   198 GRGDKHSPYHSQEETYCHEIVYLDMKTKVWHRPFTAGKVPVGRRSHSMFVYNKLIYVFGGYNGLL 262
            |.|.|          ...|:..|...| |....:..|                   ||.|:|
Zfish   163 GYGPK----------LLREVGDLQSFT-VDEASWADG-------------------VFWGWN--- 194

  Fly   263 DQHFNDLYTFDPRTKLWNLIR 283
                |:.:.|||..:.|..::
Zfish   195 ----NETHQFDPERRSWTEVQ 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12081	NP_001259343.1	KELCH repeat	13..69	CDD:276965
		Kelch_6	13..60	CDD:290672
		KELCH repeat	78..125	CDD:276965	15/52 (29%)
		Kelch_1	78..117	CDD:279660	12/44 (27%)
		KELCH repeat	128..170	CDD:276965	11/44 (25%)
		Kelch_3	137..188	CDD:290151	14/53 (26%)
		KELCH repeat	180..236	CDD:276965	14/55 (25%)
		Kelch_3	192..248	CDD:290151	11/55 (20%)
		Kelch_5	237..276	CDD:290565	8/38 (21%)
klhdc1	XP_021336373.1	KELCH repeat	37..89	CDD:276965	15/51 (29%)
		Kelch_5	37..75	CDD:316377	10/37 (27%)
		NanM	91..>210	CDD:330881	38/158 (24%)
		KELCH repeat	93..143	CDD:276965	12/51 (24%)
		KELCH repeat	146..210	CDD:276965	23/101 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D933937at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010