DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12081 and rabepk

DIOPT Version :9

Sequence 1:	NP_001259343.1	Gene:	CG12081 / 31799	FlyBaseID:	FBgn0030053	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	XP_002941691.1	Gene:	rabepk / 100492747	XenbaseID:	XB-GENE-1009616	Length:	364	Species:	Xenopus tropicalis

Alignment Length:	289	Identity:	77/289 - (26%)
Similarity:	124/289 - (42%)	Gaps:	38/289 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 EPIDVHALNAHTMRW-TLVPQQLDDAGVPLKYPLVPFQRYGHTVV-------AYKDRIYIWGGRN 97
            ||.|:    ..|..| .|||:   ..|        |..|.|||.:       :.|.::.:.||.:
Frog     8 EPEDL----PKTSTWYALVPR---GEG--------PSARVGHTCMYVPSSEDSSKGKVLVLGGAD 57

  Fly    98 DENLCNTLYCFDPKTAQWSRPQVTGCLPGARDGHSACVIGNS---MYIFGGFVDEINEFSSDVHS 159
            .....:.:|..|....:|..|.:.|.||  |..|::.:.|.|   :::|.|  .|..|..:.|..
Frog    58 PSGCFSDIYMIDLDNHEWDNPDLEGLLP--RYEHASFISGRSPGNIWVFAG--AEQAENRNCVQV 118

  Fly   160 LNLDTMEWRYVQTFGVPPSYRDFHASVAYEQERMYIFGGRGDKHSPYHSQEETYCHEIVYLDMKT 224
            ||.....|:..:..|.|||.|.||.|.|..::::|:||| |:|.:...:....|.:     |...
Frog   119 LNPGMPSWKSPKVGGTPPSPRTFHTSSASIEDKLYVFGG-GEKGAEPVTDTNLYIY-----DAAN 177

  Fly   225 KVWHRPFTAGKVPVGRRSHSMFVYNKLIYVFGGYNGLLDQHFNDLYTFDPRTKLWNLIRANGKAP 289
            ..|.:|.|:|..|..|..|.:......:||.||..|  ...|.|::..|..|..|..::..|..|
Frog   178 MTWTQPVTSGDPPQARHGHVVTAVGSKLYVHGGMAG--STFFKDMFCIDTDTMKWECLKTKGDLP 240

  Fly   290 TARRRQCAIVMGTRMFLFGGTSPRSGSSS 318
            .|.....::...:.:::|||.:....::|
Frog   241 PACAAHSSVAWKSYIYIFGGMTSTGATNS 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12081	NP_001259343.1	KELCH repeat	13..69	CDD:276965	9/28 (32%)
		Kelch_6	13..60	CDD:290672	7/19 (37%)
		KELCH repeat	78..125	CDD:276965	12/53 (23%)
		Kelch_1	78..117	CDD:279660	10/45 (22%)
		KELCH repeat	128..170	CDD:276965	12/44 (27%)
		Kelch_3	137..188	CDD:290151	18/53 (34%)
		KELCH repeat	180..236	CDD:276965	17/55 (31%)
		Kelch_3	192..248	CDD:290151	15/55 (27%)
		Kelch_5	237..276	CDD:290565	11/38 (29%)
rabepk	XP_002941691.1	PLN02193	<9..307	CDD:177844	76/288 (26%)
		KELCH repeat	31..83	CDD:276965	11/51 (22%)
		KELCH repeat	86..128	CDD:276965	12/43 (28%)
		PLN02153	127..>275	CDD:177814	41/151 (27%)
		KELCH repeat	139..189	CDD:276965	17/55 (31%)
		KELCH repeat	193..240	CDD:276965	13/48 (27%)
		KELCH repeat	243..283	CDD:276965	4/27 (15%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D933937at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1494
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.950