DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12081 and klhdc9

DIOPT Version :9

Sequence 1:	NP_001259343.1	Gene:	CG12081 / 31799	FlyBaseID:	FBgn0030053	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	XP_004919401.1	Gene:	klhdc9 / 100486977	XenbaseID:	XB-GENE-997349	Length:	346	Species:	Xenopus tropicalis

Alignment Length:	320	Identity:	67/320 - (20%)
Similarity:	109/320 - (34%)	Gaps:	83/320 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VHLDGGPQRVNHAAVGVGDFIYSFGGYCTGYD--YRYNEPIDVHALNAHTMRWTLVPQQLDDAGV 67
            |.::.|.:|.:|....:||......|   |:|  .|.:......::......|...|......|:
Frog    65 VSVESGFRRSHHDGALLGDRWLCVAG---GWDGTRRVSSVFSYDSVEGEWALWAEGPTNNPPVGL 126

  Fly    68 PLKYPLVPFQRYGHTVVAYKDR----IYIWGGRNDENLCNTLYCF--DPKT-AQWSRPQVTGCLP 125
            .           .||.....|.    |...||...:....::|..  :|.| ..|.:.:|:  ..
Frog   127 S-----------SHTCTKISDYELRVIGREGGSRTQRRYASVYSLRVNPSTRTYWYKEEVS--RT 178

  Fly   126 GARDGHSACVI----------GNSMYIFGG----FVDEINEFSSD-VH-----SLNLDTMEWRYV 170
            .:|.||||.::          |.|:|:|||    .:|...|:|.: :|     ...|.....|.|
Frog   179 ASRSGHSATLLPTDTKQGKKGGYSLYVFGGRDSAAIDIAGEWSKEKIHVSATPCPRLTEQLARLV 243

  Fly   171 QTFG----VPPSYRDFHASVAYEQERMYIFGGRGDKHSPYHSQEETYCHEIVYLDMKT--KVWHR 229
            .|.|    .|.|.|  |.|.|.....:.::||     .......:..|:::...|.:|  :.|..
Frog   244 ATEGAARSAPKSLR--HQSCAVIGPFLVVYGG-----ETLTKSRDAVCNDLYIYDTRTSPRCWSH 301

  Fly   230 PFTAGKVPVGRRSHSMFVYNKLIYVFGGYNGLLDQHFNDLYTFDPRTKLWNLIRANGKAP 289
             |...:....|..|.:.:.|..:|:.||:.                        |:||.|
Frog   302 -FPGSERQHKRVGHRICLLNDRLYLVGGFG------------------------ADGKTP 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12081	NP_001259343.1	KELCH repeat	13..69	CDD:276965	11/57 (19%)
		Kelch_6	13..60	CDD:290672	9/48 (19%)
		KELCH repeat	78..125	CDD:276965	11/53 (21%)
		Kelch_1	78..117	CDD:279660	10/45 (22%)
		KELCH repeat	128..170	CDD:276965	17/61 (28%)
		Kelch_3	137..188	CDD:290151	20/64 (31%)
		KELCH repeat	180..236	CDD:276965	11/57 (19%)
		Kelch_3	192..248	CDD:290151	9/57 (16%)
		Kelch_5	237..276	CDD:290565	6/38 (16%)
klhdc9	XP_004919401.1	KELCH repeat	21..64	CDD:276965
		Kelch_1	72..111	CDD:366584	8/41 (20%)
		KELCH repeat	73..122	CDD:276965	10/51 (20%)
		KELCH repeat	126..178	CDD:276965	11/64 (17%)
		KELCH repeat	234..308	CDD:276965	18/81 (22%)
		Kelch_5	257..294	CDD:372758	8/43 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D933937at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010