Protein Alignment Vps11 and VPS11

DIOPT Version :9

• Sequence 1: NP_730776.1
• Gene: Vps11 / 317987
• FlyBaseID: FBgn0052350
• Length: 830
• Species: Drosophila melanogaster
• Sequence 2: NP_027676.1
• Gene: VPS11 / 815065
• AraportID: AT2G05170
• Length: 932
• Species: Arabidopsis thaliana
• Alignment Length: 983
• Identity: 211/983 - (21%)
• Similarity: 371/983 - (37%)
• Gaps: 276/983 - (28%)

  Fly    23 KIPN--TAEISCYCFPESKSSTEERNIKLVICDKNRNILIYLSNWECITFKSPSTR--------- 76
            |||.  |.:|.|                   |...|..::..||...::|.....:
plant    17 KIPEDVTGDIQC-------------------CSSGRGKVVIGSNDGSVSFLDRGVKFDSGFQAHS 62

  Fly    77 -KAIALCSLTSNNSLATVTPD-----INNGIHIDIFDLNRLTKK---QAAP-------IIASAYT 125
             ..:.|..|...|.|.||..|     ..:|:.:.:|||:::.::   .:||       |..:.:.
plant    63 SSVLFLQHLKQRNFLVTVGEDEQISPQQSGMCLKVFDLDKVQEEGTSSSAPECIGILRIFTNQFP 127

  Fly   126 QPSSTPLCLNADVIDDKLFALAIGLGNGDILLHYGKITKNFSANIRQHTVSGNAVNGIHFDFKTQ 190
            :...|...:..:|  ..:..:||||.||.|....|.|.:......:......:|:.|:.|....|
plant   128 EAKITSFLVLEEV--PPILLIAIGLDNGCIYCVKGDIARERITRFKLQVDGRSAITGLGFRMDGQ 190

  Fly   191 PLDTTQIMFVTCVQGVYCFMLKEKCIMDTKF-VLDNDKGNLNYRSIMCKAGGGEINDSMLVVGRA 254
            .|    ::|....:.|..|.::.:   ..|. .||:..|::|..::.        :.|.|:|||.
plant   191 AL----LLFAVTPESVNLFSMQAQ---PPKLQTLDHIGGSVNTVTMS--------DRSELIVGRP 240

  Fly   255 DAVYCYTPEGRGPCFAIEGAKECLAWVGHYLIVGVKNSNLKQNATTLIVLDTENKIIVFQRQFQE 319
            :|||.|..:|||||:|.||.|:.:.|...||:..:.:|  |...|...|.|..|::|.:.....:
plant   241 EAVYFYEVDGRGPCWAFEGEKKFMGWFRGYLLCVIDDS--KTGNTVFNVYDLRNRLIAYSIVVDK 303

  Fly   320 LFYVISE-NNFCYIVTNSGDTDACNMLMLEKNSIDVNIRLLVEKHMYNIALRLLHREGYTSSPET 383
            :..::.| .|...|..:.      ::|.:.:..::..:.:|.:|::|.:|:.|:..: :..:..|
plant   304 VSNMLCEWGNIILIKADK------SLLCITEKDMESKLDMLFKKNLYTVAINLVQSQ-HADAAAT 361

  Fly   384 ALVRFQYGNHLLQKGDFSRATQEFIKTIGFIKPYAVISKLLYSR--YNTYLLNYLTEWKKKNESS 446
            |.|..:||:||..|.||..|..::|.|||:::|..||.|.|.::  ||  |.|||.:..:|..:|
plant   362 ANVMRKYGDHLYGKQDFDEAMLQYINTIGYLEPSFVIQKFLDAQRIYN--LTNYLEKLHEKGLAS 424

  Fly   447 SCHTRLIECCI--------------KRDQI--------------------EHEM----------- 466
            ..||.|:..|.              |.|.|                    ||.|
plant   425 KDHTTLLLNCYTKLKDVEKLNTFIRKEDGIGELKFDVETAIRVCRAANYHEHAMYVAKKAGKHEW 489

  Fly   467 ----------QQDDFKHYKS---PAK------------IKH--LATLSKMYFACT---------- 494
                      ..|:...|.|   |::            |:|  ..|:..:...||
plant   490 YLKILLEDLGNYDEALQYVSSLEPSQAGVTIEQYGKILIEHKPKETIDILMRLCTEQGIPNGVFL 554

  Fly   495 -----PSNQVPVEEEH---LLHQLLEY------GPASLAVD---LTTYLN-NITFENVKESKNIL 541
                 |.:.:.|..:|   |:|.|..|      .||...::   |..||: ::.|.::..|:|.|
plant   555 SMLPSPVDFITVFVQHPHSLMHFLERYAEIVQDSPAQAEINNTLLELYLSRDLNFPSISLSENGL 619

  Fly   542 SFCSILADHNDYCAKMLAKIIEAFPV--------------CDEKLLFYLLVFYFKLWRLDKVTSS 592
            .  ..|.||:     :.|.:.:|.|.              |.|:          :...|:.:..:
plant   620 D--KDLIDHS-----VAAAVSKADPEKKTNADSKDAMEKDCTER----------QQKGLELLKMA 667

  Fly   593 FVSDFIKTHSLRMDKTIIVSRLYTFFNVTQRIHGHQKNTGTLHNETIDKCIEN-----LI----- 647
            :.|| ::.....:|..:|:..:.:|.:....::...|    .:.|.|...::|     ||
plant   668 WPSD-LEQPLYDVDLAVILCEMNSFKDGLLYLYEKMK----FYKEVIACYMQNHDHEGLIACCKR 727

  Fly   648 ----KNNPDVALNENLSKRSFLMMLKSSCSTEEIKAI-------KIKP----------------- 684
                ....|.:|..:|.|  :...:...| |:|:|.:       .|.|
plant   728 LGDSSKGGDPSLWADLLK--YFGEIGEDC-TKEVKEVLTYIERDDILPPIIVLQTLAKNPCLTLS 789

  Fly   685 IFKDRLLRSIVDSA----NELKLVENFNEKIKRSRSMLSLYTNNPIEFRNDKCDICREMLSMQSI 745
            :.||.:.|.:...:    .:.:.||.:.|..|..|..:.....|...|:..||..|...|.:.::
plant   790 VIKDYIARKLEQESKIIEEDRRAVEKYQETTKNMRKEIEDLRTNARIFQLSKCTACTFTLDIPAV 854

  Fly   746 YFLCQHSFHEECL------------NYKSTKRQEKFLCIICKTRNLLSPKHSSNFSCDSSDTIAV 798
            :|:|.||||:.||            .|:|....::.|....|.::|...:...     |.|..:|
plant   855 HFMCMHSFHQRCLGDNEKECPECAPEYRSVMEMKRSLEQNSKDQDLFFQQVKG-----SKDGFSV 914

  Fly   799 LAKIVSIG 806
            :|:....|
plant   915 IAEYFGKG 922

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps11	NP_730776.1	zf-RING_5	732..776	CDD:291308	15/55 (27%)
VPS11	NP_027676.1	Clathrin	392..531	CDD:395512	28/140 (20%)
		Clathrin	<656..747	CDD:421262	16/107 (15%)
		RING-H2_Vps11	840..880	CDD:319602	12/39 (31%)
		VPS11_C	881..923	CDD:403597	10/47 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2114
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	173	1.000	Inparanoid score	I1516
OMA	1	1.010	-	-		QHG54534
OrthoDB	1	1.010	-	-		D429638at2759
OrthoFinder	1	1.000	-	-		FOG0005040
OrthoInspector	1	1.000	-	-		oto4223
orthoMCL	1	0.900	-	-		OOG6_102537
Panther	1	1.100	-	-	LDO	PTHR23323
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3565
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.840