Protein Alignment Vps11 and Vps11

DIOPT Version :10

• Sequence 1: NP_730776.1
• Gene: Vps11 / 317987
• FlyBaseID: FBgn0052350
• Length: 830
• Species: Drosophila melanogaster
• Sequence 2: XP_312259.6
• Gene: Vps11 / 1273295
• VectorBaseID: AGAMI1_005678
• Length: 1089
• Species: Anopheles gambiae
• Alignment Length: 908
• Identity: 223/908 - (24%)
• Similarity: 381/908 - (41%)
• Gaps: 202/908 - (22%)

  Fly     3 ISVFEWKKVDLFNII----------VVPFVKIPNTAEISCYCFPESKSSTEERNIKLVICDKNRN 57
            :::|||:|.:.|::.          .:...||..||..|..               :||||.|..
Mosquito     1 MAIFEWRKFNFFDLRQGVDKDNVSGALQGAKITATANGSSL---------------IVICDSNGY 50

  Fly    58 ILIYLSNWECITFKSPSTRKAIALCSLTS-NNSLATVTPDINNGIHIDIFDLNRLTKKQAAPIIA 121
            |..:...|..|:||  ....:|.||.:.. ||.|.||..|| ||....:::|::|:....|..:.
Mosquito    51 IHTFSRTWSAISFK--GHEGSILLCDIAKPNNLLVTVGEDI-NGPSFKVWNLSKLSATNGAQCLR 112

  Fly   122 SAYTQPSSTPLCLNADVIDDKLFALAIGLGNGDILLHYGKITKNFSANIRQHTVSGNAVNGI--- 183
            :..|. .|.|..|   .:.|....:|||...|:|.|:.|.|:::.|..::|.|...:.:.||
Mosquito   113 TVRTM-VSVPTAL---AVSDGGQFMAIGFAQGNISLYRGDISRDRSKTLKQLTAGTSDIAGIAFK 173

  Fly   184 HFDFKTQPLDTTQIMFVTCVQGVYCFML--KEKCIMDTKFVLDNDKGNLNYRSIMCKAGGGEIND 246
            |....||       |||....|||.:.|  ::|   :.:.:|...|     :.:.|.|.....|:
Mosquito   174 HCHKHTQ-------MFVCSNSGVYVYNLHSRDK---EIRVILATMK-----KPVGCCALQTGHNE 223

  Fly   247 SMLVVGRADAVYCYTPEGRGPCFAIEGAKECLAWVGHYLIVGVKNSNLKQNATTLIVLDTENKII 311
            ...:||..|||||||.:|||||:|:||.|..|.|...:|:|.::|.. .....||.|:|.:||.|
Mosquito   224 GHFMVGLEDAVYCYTSDGRGPCYALEGNKTLLHWYRSHLLVVMRNPR-SPGGFTLTVIDIQNKFI 287

  Fly   312 VFQRQFQELFYVISENNFCYIVTNSGDTDACNMLMLEKNSIDVNIRLLVEKHMYNIALRLLHREG 376
            ||....:|:..:::|...|||:     |:...:|.|::..:...:.:|.:|::|:||:|:.....
Mosquito   288 VFTSPIEEVSAILTEFGTCYIL-----TEGKQILHLDEKDLQSKLNVLFKKNLYDIAVRIAKCNQ 347

  Fly   377 YTSSPETALVRFQYGNHLLQKGDFSRATQEFIKTIGFIKPYAVISKLLYSRYNTYLLNYLTEWKK 441
            |.:.....:.: |||:||..||||:.|.:::.||||:::|..||.:.|.:|:..||.:||.....
Mosquito   348 YDAEGLAGIFK-QYGDHLYSKGDFAGAVEQYAKTIGYLEPSYVIQRFLDARHIHYLTDYLQTIHA 411

  Fly   442 KNESSSCHTRLIECCIKR----DQIEHEMQQD----------------DFKHYKSPAKI-----K 481
            :..:::.||.|:..|..|    .|::..::.|                |..:.:...::     |
Mosquito   412 QGRATADHTTLLLNCFTRLDRTTQLKEFLKNDQKSNLFDIDVAIKVCRDASYVEEALQLAKAHRK 476

  Fly   482 HLATLSKM---------------YFACTPSNQVPVEEEHLLHQLLEYGPASLA------VDL--- 522
            |.|.||.:               ..||..:.          |.:..||...:|      :.|
Mosquito   477 HDACLSILTEDMGQFEEALNYIESLACAEAE----------HSIKRYGSVLMANCPSRTIALLKK 531

  Fly   523 --TTYLNNITFENVKESKNILSFCSILADHN--------------------DYCAKMLAKIIEAF 565
              |.|..|   .|..:.::.|:...:|||.|                    :.....|..:|...
Mosquito   532 LCTEYATN---RNSTQGRDALTVADLLADLNLNDERGHGNPEEFIHLFDDTELLIDFLEHLIRFV 593

  Fly   566 PVCDEKLLFYLLVFYFKLWRLDKVTSSFVSDFIKTHSLRMDK--TIIVSRLYTFFNVTQRIHGHQ 628
            |...:.:...|:..|...|:........:.|.:|.::.|.||  .:...|::.|:.....::...
Mosquito   594 PASSQCVYSTLIEHYLYRWKESTAVEEKLLDLLKFNTDRYDKNHALAQCRMHEFWPGVMYLYEED 658

  Fly   629 KNTGTLHN------------ETIDKCIENLIKNNPDVAL-------NENLSKRSFLMMLKSSCST 674
            |    |::            |.:..|...|..||..:.|       |:..:.......:....|.
Mosquito   659 K----LYHLIIRHYLRHRQYEELLACCRKLAHNNASLWLLTLNGLKNDAQAPPHLFNQILQVISQ 719

  Fly   675 EEIKA----------------IKIKPIF------KDRLLRSIVDSANELKLVENFNEKIKRSRSM 717
            :.::|                :.:|..|      :...:||..:.|...:     .|.:...|.:
Mosquito   720 KRLQAPLQVLDCLAVDNGPNFLSVKEYFMQVFQKEQDTIRSEEEQARAYR-----EESVSIKRYI 779

  Fly   718 LSLYTNNPIEFRNDKCDICREMLSMQSIYFLCQHSFHEECL-NYKSTKRQEKFLCIICKTRNL 779
            ..|...| :||:|..||.|::.|||.:::|||:||:|::|: :|..|:|.    |.:|...|:
Mosquito   780 KHLQEGN-VEFQNTTCDACKQPLSMPALFFLCKHSYHQDCIRSYTDTERD----CPVCNKNNM 837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps11	NP_730776.1	RING-H2_Vps11	731..777	CDD:438349	18/46 (39%)
Vps11	XP_312259.6	None