Protein Alignment Vps11 and vps11

DIOPT Version :10

• Sequence 1: NP_730776.1
• Gene: Vps11 / 317987
• FlyBaseID: FBgn0052350
• Length: 830
• Species: Drosophila melanogaster
• Sequence 2: NP_001120879.1
• Gene: vps11 / 100101673
• XenbaseID: XB-GENE-922526
• Length: 914
• Species: Xenopus tropicalis
• Alignment Length: 899
• Identity: 203/899 - (22%)
• Similarity: 349/899 - (38%)
• Gaps: 187/899 - (20%)

  Fly    49 LVICDKNRNILIY---LSN-W------ECITFKSPSTRKAIALCSLTSNNSLATVTPDINNGIH- 102
            |.:||..|..|::   ..| |      :..:|::...| ...|..|..:|.|.:|..| ..||:
 Frog    34 LTVCDSGRGSLLFGDMTGNIWFLPRSLQLTSFQAYKLR-VTHLHQLKQHNILVSVGED-EEGINP 96

  Fly   103 -IDIFDLNRLTKKQAAPIIASAYTQ-PSSTPLCLNADVIDDKLFALAIGLGNGDILLHYGKITKN 165
             :.:::|.:  :...:|:....:.. |.:.|..::...:.:.|..:|||..:|.::|..|.||::
 Frog    97 LVKVWNLEK--RDGGSPLCTRIFPAIPGNKPTVVSCITVHENLNFMAIGFADGSVVLTKGDITRD 159

  Fly   166 FSANIRQHTVSGNAVNGIHFDFKTQPLDTTQIMFVTCVQGVYCFMLKEKCIMDTKFVLDNDKGNL 230
            ..:..:........|.|:.|   .|...||. :||...:.|..:.|.:|....|:  ||:....|
 Frog   160 RHSKTQILQEGSYPVTGMAF---RQTGKTTH-LFVVTTENVRSYELTQKDYPYTE--LDSHGCGL 218

  Fly   231 NYRSIMCKAGGGEINDSMLVVGRADAVYCYTPEGRGPCFAIEGAKECLAWVGHYLIV-------- 287
            .     |.|......|...||...:.||.|.|:.||||||.||.|..:.|...|||:
 Frog   219 R-----CSALSDPSQDLQFVVAGNECVYLYQPDERGPCFAFEGQKMIVHWYRGYLIIVSKDRLEF 278

  Fly   288 -GVKNSNLKQNATTLIVLDTENKIIVFQRQFQELFYVISENNFCYIVTNSGDTDACNMLMLEKNS 351
             |....:...:..||.:.|..||:|.:...|.|:..|::|....|::|..|...|     |.:..
 Frog   279 AGRAGDSQAMDRQTLTIYDLSNKLIAYSSAFTEVVDVLAEWGSLYVLTRDGLLHA-----LHEKD 338

  Fly   352 IDVNIRLLVEKHMYNIALRLLHREGYTSSPETALVRFQYGNHLLQKGDFSRATQEFIKTIGFIKP 416
            ....:.:|.:|:::.:|:.|...:...|...:.:.| |||:||..|||...|.|::|:|||.::|
 Frog   339 TQTKLEMLFKKNLFVMAISLAKSQHLDSDGLSEIFR-QYGDHLYNKGDHDGAIQQYIRTIGKLEP 402

  Fly   417 YAVISKLLYSRYNTYLLNYLTEWKKKNESSSCHTRLIECC-------------IKRDQIE----- 463
            ..||.|.|.::....|..||.....::.:::.||.|:..|             ||..:.|
 Frog   403 SYVIRKFLDAQRIHNLTAYLQALHLQSLANADHTTLLLNCYTKLKDSARLEEFIKASEGEVRFDV 467

  Fly   464 -------------------------HE----MQQDDFKHYKSPAKIKHLATLSKMYFACTPSN-- 497
                                     ||    :|.:|.|:::     :.|..:.::.|....||
 Frog   468 EIAIKVLRQAGYHSHALYLAEKHAHHEWYLKIQLEDIKNFQ-----EALQYIGRLPFPQAESNMK 527

  Fly   498 --------QVPVEEEHLLHQLLEYGPASLAVDLTTYLNNITFENVKESK-NILSFCSILADHNDY 553
                    .||.|...||:.|....|                :|.:.|: |...|..|.|::...
 Frog   528 RYGKTLMCHVPNETTQLLNNLCTSFP----------------QNGEGSRANPEEFIPIFANNPSE 576

  Fly   554 CAKMLAKIIEAFPVCDEKLLFYLLVFYFKLW--RLDKVTSSFVSD----FIKTHSLR--MDKTII 610
            ....|..:|:......:.:...||....:.|  .||....:.:.|    .:|:...:  .||.::
 Frog   577 LKTFLEHMIKEHSDSPQGVYDTLLELRLQNWAHELDPQLKNQLHDDAISLLKSGRFKNVFDKALV 641

  Fly   611 VSRLYTFFN-----------VTQRIHGHQKNTGTLHNETIDKC--------------IENLIKNN 650
            :.:::.|.|           ..|.:|.|.:|  ..:.:.|:.|              :....:..
 Frog   642 LCQMHNFQNGVLYLYEQGKLFQQIMHYHMQN--DQYQKVIEACERYGEQETCLWEQALSYFARKE 704

  Fly   651 PD----VAL------NENLSKRSFLMMLKSSCSTEEIKAIKIKPIFKDRLLRSIVDSANELKLVE 705
            .|    :|:      |.||.....::...:..||..:..|:...|.|.:.|...::  .:.:.|.
 Frog   705 EDCKEYIAMVLGHIENRNLMPPLLVVQTLAHNSTATLSVIREYLINKMQKLSQKIE--EDERTVH 767

  Fly   706 NFNEKIKRSRSMLSLYTNNPIEFRNDKCDICREMLSMQSIYFLCQHSFHEECLNYKSTKRQEKFL 770
            .:.|...|.|..:.....:|..|:..||.||...|.:.|::|||.||||:.|.   .:..:....
 Frog   768 QYREDTARIRREIQELRTSPKIFQKTKCSICSSSLELPSVHFLCGHSFHQHCF---ESYAENDVD 829

  Fly   771 CIIC-----KTRNLLSPKHSSNFSCD--------SSDTIAVLAKIVSIG--NKL 809
            |..|     |..:::..:.......|        |||..:|:|.....|  |||
 Frog   830 CPTCLPENRKVLDMIQAQEEKRELYDQFQHQLKHSSDGFSVVADYFGRGVFNKL 883

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vps11	NP_730776.1	RING-H2_Vps11	731..777	CDD:438349	17/50 (34%)
vps11	NP_001120879.1	Clathrin	399..517	CDD:459884	21/122 (17%)
		CLH	559..705	CDD:128594	24/147 (16%)
		RING-H2_Vps11	793..836	CDD:438349	16/45 (36%)
		VPS11_C	837..880	CDD:463590	8/42 (19%)