Protein Alignment CG12065 and Upp2

DIOPT Version :10

• Sequence 1: NP_001368976.1
• Gene: CG12065 / 31798
• FlyBaseID: FBgn0030052
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: XP_011237507.1
• Gene: Upp2 / 76654
• MGIID: 1923904
• Length: 416
• Species: Mus musculus
• Alignment Length: 358
• Identity: 66/358 - (18%)
• Similarity: 118/358 - (32%)
• Gaps: 125/358 - (34%)

  Fly   221 IELRILEETSAPPSRPPRDGYIIYCYGDCNRKFEEALMAQRKTGDGDNLMKAIWLDMYTEQLISL 285
            |.:..::..||.....|....::..:|.|     ..::...||       .:.|..::.
Mouse    45 IRVHTVQHRSASCPLLPNSSLLLCFHGSC-----RTMVYSSKT-------VSHWSTLFC------ 91

  Fly   286 EESQFESPPLTQEKVLELIE---QAYPNPVSPEDLAKDYGWSEQDVLLVIKSLQERGLI-----K 342
             .||..:|.|.:.::.:.|:   :.:|          |.||.      ::.::|....|     :
Mouse    92 -SSQTPAPSLLEPRLKKEIDWCGETHP----------DCGWP------LLAAVQSMASILPASNR 139

  Fly   343 SM--EYNAYTR----------IHHEDKEIKVVKQMPTIASNKQPTIAIITAQYCEKLAVDAMLEN 395
            ||  :.|.|.|          :...|::|.....:.|...|                 :.||..:
Mouse   140 SMRPDKNTYERKRSVYVKNPYLEGMDEDILYHLDLGTKTHN-----------------LPAMFGD 187

  Fly   396 KETFVRYTTVDSDPNLTNSLRKSKKKRRFGESNVYTLGNIGAHRIVSTKLPSVGSNREAMTATG- 459
                |::..|...||...:..:...|....|.:...:.:|.|           |::|..|..||
Mouse   188 ----VKFVCVGGSPNRMKAFAQFMHKELRLEGDGEDIEDICA-----------GTDRYCMFKTGP 237

  Fly   460 -----------------NTTTRLLGTFQKVDYVFI-------VGVAGGVPHYTD------YK--- 491
                             :...:||......|...|       :|:|.|....||      :|
Mouse   238 VLSVSHGMGIPSISIMLHELIKLLHHAHCCDVTIIRIGTSGGIGIAPGSVVITDTAVDSFFKPRF 302

  Fly   492 KHVRLGDVVI--SYVDKQRA--LISNSKEKPYV 520
            :.|.|.:||.  :.:||:.|  |.:.|:|.|.|
Mouse   303 EQVILDNVVTRSTELDKELANDLFNCSREIPNV 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12065	NP_001368976.1	COG2512	290..>342	CDD:442002	9/59 (15%)
		MtnN	375..697	CDD:440538	37/184 (20%)
Upp2	XP_011237507.1	UP_hUPP-like	166..399	CDD:350163	40/202 (20%)