Protein Alignment CG12065 and H14E04.2

DIOPT Version :10

• Sequence 1: NP_001368976.1
• Gene: CG12065 / 31798
• FlyBaseID: FBgn0030052
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: NP_741095.1
• Gene: H14E04.2 / 175356
• WormBaseID: WBGene00019199
• Length: 582
• Species: Caenorhabditis elegans
• Alignment Length: 653
• Identity: 188/653 - (28%)
• Similarity: 323/653 - (49%)
• Gaps: 124/653 - (18%)

  Fly    83 VVMTPRGKTANSTVILIERKLVDEINDRVHVAGGDHTGIIINKDTVAGQKSASKAAA-LSLEFRV 146
            ||:||:.:.::..::.|.|:...:.:..:|:.||.:.|:|||:   ..:||..::.| :||.|.|
 Worm     9 VVLTPKKQDSDHNIVKIHREETAKSDKVLHIGGGSYAGLIINR---YEEKSNFESTADVSLSFSV 70

  Fly   147 FLVSANTGKHSQESRTLRFWFRDWLTNEEKQAHIAQDFFKELVSPQDFPRDYVGFIKKIMKLLQH 211
            .|.:.|..|..||.|:|.|..|..:..:..:. :...|||.|:|  :.|.|||.|:|:.|.|||.
 Worm    71 HLSNKNHQKQVQEKRSLFFKLRKSVELDVGRL-VVHKFFKNLLS--NLPGDYVSFMKRAMTLLQK 132

  Fly   212 GYSEIQSIEIELRILEET---SAPPSRPPRDGYIIYCYGDCNRKFEEALMAQRKTGDGDNLMKAI 273
            .|:||..:.|:.:|:||:   :.|.:                .::|.:     |.|
 Worm   133 DYTEIVELVIDYKIVEESDQVTIPDA----------------TQYETS-----KRG--------- 167

  Fly   274 WLDMYTEQLISLEESQFESPPLTQEKVLELIEQAYPNPVSPEDLAKDYGWSEQDVLLVIKSLQER 338
                        ::|..|...:|...|.|::|.|:||.:....:::....|:::.|..:..|:..
 Worm   168 ------------KDSGSELEEVTVGHVQEILEHAFPNGLPTCAISECLRCSDEETLAFLAELETS 220

  Fly   339 GLIKSMEYNAYTRIHHE--DKEIKVVKQMPTIAS-------NKQPTIAIITAQYCEKLAVDAMLE 394
            |:::.:| :.:.|:..:  |:.|:..:.....||       ::|||:|||:..:.||.|:||::|
 Worm   221 GIVRMVE-DEWIRVDTKKVDESIEAHRNAAAAASTSAGNGLSEQPTVAIISCLFVEKQAIDALIE 284

  Fly   395 NKETFVRYTTVDSDPNLTNSLRKSKKKRRFGESNVYTLGNIGAHRIVSTKLPSVGSNREAMTATG 459
            ...|..:|                   :..|:|||||||.|||||:|:|||..:|.:|||:|:.|
 Worm   285 ESSTIHKY-------------------KSGGDSNVYTLGRIGAHRVVATKLALIGDSREAITSAG 330

  Fly   460 NTTTRLLGTFQKVDYVFIVGVAGGVPHYTDYKKHVRLGDVVISYVDKQRALISNSKEKPYVYLYK 524
            :.||||||.||.:::||||||||.|||:||...|.|||||::            |..:|:.|:|.
 Worm   331 SITTRLLGNFQNIEHVFIVGVAGAVPHFTDATLHARLGDVIV------------SASRPHQYVYA 383

  Fly   525 ------------SGEDVKTYFPVNDSLQQIAESLQANMQVKRPWEDYLNQAQQALAQKT-DADFN 576
                        :|..::.:...:.::::|.|:  ...::...|....::|...|.... |.::.
 Worm   384 HDLLFNRQTEQITGFAIRNWDADDKTIEKIVET--GGEELLSAWNSATDEAIALLTSSAGDVEWK 446

  Fly   577 RPDARTDKLFMNIGNNEVIEVAHPIAADEVDGVNRLRLHLGPIGSGRDLVRSD----------EL 631
            .|...||.|.|.:....|:.:.|| .||...|.   .:|||.:|:...:.:.:          ::
 Worm   447 APPTSTDVLAMTVSKGNVVVMPHP-NADTKTGP---EIHLGTVGAMSAMKKYEKWDGEEDSLAKV 507

  Fly   632 RTQFARKYGLLATDVEMSSVLDSIIGNCRESFILVKGIADYKDGTST--RKWQNFAAISAASVVK 694
            |..||..:|:...|....||:.:::|:|..|:.|::||:||..|.|.  :.||..||..||.:.:
 Worm   508 RETFAESFGIRCIDAGFDSVVGAVVGSCVRSWALIRGISDYDYGQSRAGKVWQAHAAARAAGMAR 572

  Fly   695 SVI 697
            .:|
 Worm   573 CII 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12065	NP_001368976.1	COG2512	290..>342	CDD:442002	12/51 (24%)
		MtnN	375..697	CDD:440538	111/346 (32%)
H14E04.2	NP_741095.1	MtnN	265..>385	CDD:440538	66/150 (44%)