DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32320 and spe-49

DIOPT Version :9

Sequence 1:	NP_001097472.3	Gene:	CG32320 / 317977	FlyBaseID:	FBgn0052320	Length:	767	Species:	Drosophila melanogaster
Sequence 2:	NP_001343858.1	Gene:	spe-49 / 187315	WormBaseID:	WBGene00019667	Length:	772	Species:	Caenorhabditis elegans

Alignment Length:	787	Identity:	146/787 - (18%)
Similarity:	270/787 - (34%)	Gaps:	220/787 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 LYVIGGYIVGLLMVLIWYYRNPQEACKDLN-----------GKWIFIVLLSFLLIILVRRRPA-R 151
            |.::..::.|||:....|:    ...|:||           .||..:...::...:    .|. |
Worm    36 LRLLVNFLFGLLISSSLYH----AGWKNLNFGDFDYTYGLIVKWTIVAFSTYAFAV----SPIFR 92

  Fly   152 CIAVLCL---SSLSSNQFRIAVIALCFLLAFSGPVKNIIHNTCILANTLTCEQNVLIQALMLMQR 213
            | |:.|:   :.....|:...::.:..|.  .||:.|::.|....:..:.|  ::.:|:.:...|
Worm    93 C-ALFCVLIGAFGKQGQYPFTMLVMSNLQ--EGPISNMMSNYETTSEIVMC--HIELQSKITANR 152

  Fly   214 I--INDPSHSVEEAFKTTLAEVSRLMNKLDKLLLNLERPIAQIHATFKTCTD------------- 263
            :  :..|   :||..:..:|:..|.|..:.:....|..|..::..|.||..|
Worm   153 VALLTGP---LEELIEKLMAKGIRAMKAVSRETRALITPFMELLKTEKTKIDKKIEIERGQLEDI 214

  Fly   264 ----------W-----------------LFLQKDHYD-YKMGSP-----YNRCL--KAGNLSIAH 293
                      |                 |...:|..| ..:|.|     :...|  |..:....:
Worm   215 EKRKQRILKMWEKSMNRSLTEEDQIAGELLPAEDLIDNVTIGEPPVWKKFKTPLIQKMADKMSRN 279

  Fly   294 CKREFGEGQKEC----------CKLELFLW-----FCNSLKTYTTFFDDNIQWSQMVIKDIFQRL 343
            |::.|.:|..:|          || :..:|     .|..|         |::.....::...|.:
Worm   280 CEQMFNKGIDKCRNLAAELVSSCK-DAIIWPIEAFICPKL---------NVEGVCDAVERRVQSM 334

  Fly   344 QLCFVKIRFIFITTISFDHSLKFNSTGAFSSNIDQIDEQDV------KEEFEAQRH-KLHFV--- 398
            .:|..::.                     .|::|...|:||      .||.|...: :||.|
Worm   335 NICRNQLE---------------------ESHVDPSIEKDVTDVMKLTEELEQNSNIELHSVRVE 378

  Fly   399 -------YLWLNLIIFILLLTIIYKSLC-----------FWF-------------RYLTDNDFEN 432
                   |...:|.|.|....:.:||:.           .:|             :|..|..|.|
Worm   379 TPRVAIEYRLSDLKIKIRAANLYFKSIVGVSKQIFQAFFIYFVYTIFRDSVGMIRKYQEDVAFSN 443

  Fly   433 FYITEAFEDYDDQYYQIMGLRVLPLSNCEDN---KFVKISSMRLLAKEFDTIYRSAMFLVITGIQ 494
            .::|:.|. ..|::.|..|...|...:.::.   :.:::.|:...|:....: |......|..:.
Worm   444 SFVTKEFW-MIDRFRQARGQTHLSHFSKQEKREWRVMEVFSLPTKAERSKAV-RPFFRWFILALT 506

  Fly   495 LLCICFVDYSLYSLLTLMSYHGHMIEDVKPPSYTKIVINGGGKIGDMLRDLVQAFEPRTFK---- 555
            :..|..:||.|:..|..:..........|..:...:.|.|.|.:.|.|:.:....|  |.:
Worm   507 VSVIIILDYYLFVFLDSVVESARQQVKQKASAPAGLNITGEGVLADFLKTMTSTNE--TLEVDQT 569

  Fly   556 MNTQRCLPIPGYPKYLRYVWILLLYLLAWFLVFWEPYGLRQRHRVMMYF----YPEESRRRSHDL 616
            ::.:.||..|..|.....::.|::.||..|| |...:....|..|:.||    :|..|:.|....
Worm   570 LSNEHCLLKPLAPNTDILIYWLVIPLLLSFL-FQVVFSFAIRRIVLNYFLPFMFPMRSKVRLIQF 633

  Fly   617 HDTILINR-KHFFKARC-----MEARLLNAFESTQEFKSCATWFNSRLNWYALTLYLNRFKHNPH 675
            ::..|:|| ||..:||.     ::.|.:..... .||.:..::....:
Worm   634 YNKCLVNREKHRKEARARIRFMVDRRRIETLRK-GEFSAGGSFLKQHV----------------- 680

  Fly   676 CRCLSCFTVSFIGRCCTLCNKPLNKCDNVPCGWPNCRGIYCKMCFQESNNKCVLCCL---EIDDE 737
                  |...|....|.||.:.........|....|:..:||.|.:::..||..|..   |:.|:
Worm   681 ------FERIFKTAKCFLCQEKTYARKLFYCAEVKCQSSFCKDCVEDNFGKCYSCMFIKKEVTDQ 739

  Fly   738 ---LLEP 741
               ||.|
Worm   740 KSKLLNP 746

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32320	NP_001097472.3	DC_STAMP	430..617	CDD:285077	42/197 (21%)
spe-49	NP_001343858.1	DC_STAMP	441..631	CDD:369517	42/194 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167744
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21041
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940