Protein Alignment CG32320 and DCST2

DIOPT Version :10

• Sequence 1: NP_001097472.3
• Gene: CG32320 / 317977
• FlyBaseID: FBgn0052320
• Length: 767
• Species: Drosophila melanogaster
• Sequence 2: NP_653223.2
• Gene: DCST2 / 127579
• HGNCID: 26562
• Length: 773
• Species: Homo sapiens
• Alignment Length: 707
• Identity: 167/707 - (23%)
• Similarity: 284/707 - (40%)
• Gaps: 90/707 - (12%)

  Fly    88 KSPTECRCNALLYVIGGYIVGLLMVLIWYYRNPQEACKDLNGKWIFIV----LLSFLLIILVRRR 148
            :.|:..|  |::..:||:.:||.:...:   ...|...:.:..|..:|    |.:||.:.:...|
Human    15 EEPSMAR--AVVRSVGGFTLGLSLATAY---GLLELLVEGHSPWGCLVGTLTLAAFLSLGMGFSR 74

  Fly   149 PARCIAVLCLSSLSSNQFRIAVIALCFLLAFSGPVKNIIHNTCILANTLTC-EQNVLIQALMLMQ 212
            ..|...:|.|....|.|.|..::...|.|...||..|.:.|....:..:.| .:..|.|...::|
Human    75 QVRATVLLLLPQAFSRQGRTLLLVAAFGLVLQGPCANTLRNFTRASEAVACGAELALNQTAEVLQ 139

  Fly   213 RIINDPSHSVEEAFKTTLAEVSRLMNKLDKLLLNLERPIAQIHATFKTCTDWLFLQKDHYDYKMG 277
            | ...|..|.....|....:...:.:::.|...::...:..|....:....||....|..:.::|
Human   140 R-AKQPLVSALNKIKAIARKTKEVADRVRKFFRSIMDGVKHIARALRNVWQWLLHIGDVCNSELG 203

  Fly   278 SPYNRCLKAGNLSIAHCKREFGEGQKEC----------CKL-ELFLWFCNSLKTYTTFFDDNIQW 331
            :||.:|.:..:.:...|.....:....|          |.| .|...||...|....|.
Human   204 NPYLKCARVFDDAKDSCMMVIPQAYHLCYVLMPFKLALCGLASLVQVFCVIPKYIQPFL------ 262

  Fly   332 SQMVIKDIFQRLQLCFVKIRFIFITTISFDHSLKFNSTGAFSSNIDQIDEQDVKEEFEAQRHKLH 396
            .|.:...:.|.|..  |:..|.|..|.:...|:..|::.:.|        |...:..||...|||
Human   263 RQTIGTPVIQLLNR--VRQEFEFNMTATHHFSVDLNASRSLS--------QVAMDLHEAVSMKLH 317

  Fly   397 FVYLWLNLIIFI--LLLTIIY-KSLCFWFRYLTDNDFENFYITEAFEDYDDQYYQIMGL-RVLPL 457
            .|...|.|:.|.  |||.::| ::|.:.:.||..:.::|.|||..|... :......|| .||||
Human   318 RVREALALMGFTTPLLLVLLYLQALFYRYCYLNWDHYDNIYITSRFLRM-EAVRSTAGLPTVLPL 381

  Fly   458 SNCEDNKFVKISSMRLLAKEFDTIYRSAMFLVITGIQL-LCICFVDYSLYSLLTLMSY--HGHMI 519
            |..|..:::...|: .|::.....|....|.:|..:.| |.:.|:||:::.:|.|..:  .|.::
Human   382 SAHEARRYIPPGSI-FLSQWEKFFYILETFNLIRHLLLVLFLVFLDYAVFWVLDLARHQLQGEIV 445

  Fly   520 EDVKPPSYTKIVINGGGKIGDMLRDLVQAF---EPRTFKMNTQRCLPIPGYPKYLRYVWILLLYL 581
              .:.|....:.:.|.|..|::.||||.||   :.....:.::|||..|..|....|:.|.::|.
Human   446 --ARSPVLVSLTVEGTGYAGNIYRDLVSAFDVLQQGNISILSRRCLLRPSEPDSTGYIVIGVMYG 508

  Fly   582 LAWFLVFWEPYGLRQRHRVMMYFYPEESRRRSHDLHDTILINRKHFFKA--RCMEARLLNAFEST 644
            |.:|:..:..|..|.|..:...:||...:.|...|::.:|..|.:...|  |.:..|     .:.
Human   509 LCFFITLFGSYVSRLRRVICASYYPSREQERISYLYNVLLSRRTNLLAALHRSVRRR-----AAD 568

  Fly   645 QEFKSCATWFNSRLNWYALTLYLNRFKHNPHCRCLSCFTVSF--IGRCCTLCNKPLNKCD---NV 704
            |..:|......||                  |.||..|...|  ....|..|.:|.::.|   .|
Human   569 QGHRSAFLVLASR------------------CPCLGPFVSHFWLHQAYCLGCGQPQDEGDMENTV 615

  Fly   705 PCGWPNCRGIYCKMCFQESNNKCVLCCLEIDDELLEPGNSSGNSEADFCITDNNYPQ 761
            .|..|.|:|:||..||:..:|.|.:|.        .|.:..|:.:.:...:|...||
Human   616 SCSTPGCQGLYCLTCFRLLDNTCSVCA--------SPLSYQGDLDLELDSSDEEGPQ 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32320	NP_001097472.3	DC_STAMP	430..617	CDD:462265	52/193 (27%)
DCST2	NP_653223.2	DC_STAMP	354..544	CDD:462265	52/193 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	692..773