DRSC/TRiP Functional Genomics Resources

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Protein Alignment Naa30B and NAA50

DIOPT Version :9

Sequence 1:NP_728606.1 Gene:Naa30B / 317976 FlyBaseID:FBgn0052319 Length:211 Species:Drosophila melanogaster
Sequence 2:NP_079422.1 Gene:NAA50 / 80218 HGNCID:29533 Length:169 Species:Homo sapiens


Alignment Length:124 Identity:33/124 - (26%)
Similarity:58/124 - (46%) Gaps:12/124 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    58 HDESQLKVLMGLIDKELSEPYSIYTYRYF--VYNWPDLCFFALDGDRYVGVIVCKLEAKRDGYLQ 120
            |:..|||.|     .::..|.| |..:::  |....:|...|...|..||.:.|:::..:: ..:
Human    14 HNIKQLKRL-----NQVIFPVS-YNDKFYKDVLEVGELAKLAYFNDIAVGAVCCRVDHSQN-QKR 71

  Fly   121 GYIAMLAVDAEYRKRGIGRALSEMAIDAMAIRDAAM--IVLETELSNKPALALYQSLGF 177
            .||..|...|.||:.|||..:....:: :..:|...  |.|..::||:.|:..|:..||
Human    72 LYIMTLGCLAPYRRLGIGTKMLNHVLN-ICEKDGTFDNIYLHVQISNESAIDFYRKFGF 129

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Naa30BNP_728606.1 rimI 70..194 CDD:273701 28/112 (25%)
Acetyltransf_1 99..177 CDD:278980 20/79 (25%)
NAA50NP_079422.1 RimI 10..145 CDD:223532 33/124 (27%)
Acetyl-CoA binding. /evidence=ECO:0000269|PubMed:21900231, ECO:0000269|PubMed:27484799, ECO:0000269|Ref.18, ECO:0007744|PDB:2PSW, ECO:0007744|PDB:3TFY, ECO:0007744|PDB:4X5K 77..90 6/12 (50%)
Coenzyme A binding. /evidence=ECO:0000269|PubMed:21900231, ECO:0000269|PubMed:27484799, ECO:0000269|Ref.18, ECO:0007744|PDB:2PSW, ECO:0007744|PDB:3TFY, ECO:0007744|PDB:4X5K 117..126 3/8 (38%)
Substrate binding. /evidence=ECO:0000269|PubMed:21900231, ECO:0000269|PubMed:27484799, ECO:0007744|PDB:3TFY, ECO:0007744|PDB:4X5K 138..141
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0456
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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