DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Naa30B and NAA30

DIOPT Version :9

Sequence 1:	NP_728606.1	Gene:	Naa30B / 317976	FlyBaseID:	FBgn0052319	Length:	211	Species:	Drosophila melanogaster
Sequence 2:	NP_001011713.2	Gene:	NAA30 / 122830	HGNCID:	19844	Length:	362	Species:	Homo sapiens

Alignment Length:	195	Identity:	92/195 - (47%)
Similarity:	126/195 - (64%)	Gaps:	15/195 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 ELSDKDSQEKMDLVTKNL--------PLFAEKIVLPENDTAAKSEGIHFCVFHDESQLKVLMGLI 70
            |..:::..|::.|::.:|        |...|  |.|..|..     |.:..:..|.|:..:|.||
Human   174 EQEEEEEDEQVRLLSSSLTADCSLRSPSGRE--VEPGEDRT-----IRYVRYESELQMPDIMRLI 231

  Fly    71 DKELSEPYSIYTYRYFVYNWPDLCFFALDGDRYVGVIVCKLEAKRDGYLQGYIAMLAVDAEYRKR 135
            .|:|||||||||||||::|||.|||.|:.|:..||.|||||:..:..:.:|||||||||::||:.
Human   232 TKDLSEPYSIYTYRYFIHNWPQLCFLAMVGEECVGAIVCKLDMHKKMFRRGYIAMLAVDSKYRRN 296

  Fly   136 GIGRALSEMAIDAMAIRDAAMIVLETELSNKPALALYQSLGFIRERRFLRYYLNGMDAFHLKLML 200
            |||..|.:.||.||...|...:|||||::||.||.||::|||:|::|..||||||:||..|||.|
Human   297 GIGTNLVKKAIYAMVEGDCDEVVLETEITNKSALKLYENLGFVRDKRLFRYYLNGVDALRLKLWL 361

Fly 201 200
Human 362 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Naa30B	NP_728606.1	rimI	70..194	CDD:273701	73/123 (59%)
Naa30B	NP_728606.1	Acetyltransf_1	99..177	CDD:278980	40/77 (52%)
NAA30	NP_001011713.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	38..88
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	113..182		1/7 (14%)
		RimI	209..362	CDD:223532	84/158 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157584
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0456
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S678
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1323575at2759
OrthoFinder	1	1.000	-	-		FOG0002360
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101962
Panther	1	1.100	-	-	O	PTHR45896
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3472
SonicParanoid	1	1.000	-	-		X2923
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.690