DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33791 and AT5G65750

DIOPT Version :9

Sequence 1:	NP_001027100.1	Gene:	CG33791 / 317974	FlyBaseID:	FBgn0035240	Length:	1282	Species:	Drosophila melanogaster
Sequence 2:	NP_201376.1	Gene:	AT5G65750 / 836704	AraportID:	AT5G65750	Length:	1025	Species:	Arabidopsis thaliana

Alignment Length:	1099	Identity:	477/1099 - (43%)
Similarity:	627/1099 - (57%)	Gaps:	150/1099 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 SLAR--IRRSLTLGLRGTDQHVLARQALRTIQTTSQRRGVHD----------------------L 48
            |:|:  |||:|:....|:       .|.||.....|.|..|.                      .
plant     9 SVAKLAIRRTLSQSRCGS-------YATRTRVLPCQTRCFHSTILKSKAESAAPVPRPVPLSKLT 66

  Fly    49 DSFANGCSAAYIEGLYNKWKRNPSSVDESWNELFSSNDWSSPKRSPLQVSHSRKYRRPPVERIAV 113
            |||.:|.|:.|:|.|...|:.:|:||||||:..|
plant    67 DSFLDGTSSVYLEELQRAWEADPNSVDESWDNFF------------------------------- 100

  Fly   114 KARSGERTASGGASAAPAAPPSDWKNIDDHHVIQAIIRAYQSRGHLAADLDPLGIVGPKKRTSVD 178
                  |...|.||.:|..   ..:.|.:...:..::||||..||:.|.|||||:
plant   101 ------RNFVGQASTSPGI---SGQTIQESMRLLLLVRAYQVNGHMKAKLDPLGL---------- 146

  Fly   179 GTQRHAAREVLRQHFSYIFNDLNTVFKLPSSTMIGGDQEFLS-------LKEILDRLERIYCGHI 236
             .:|....::....:.:...||:..|.|....|.|    |||       |:.||.|||:.|||.|
plant   147 -EKREIPEDLTPGLYGFTEADLDREFFLGVWRMSG----FLSENRPVQTLRSILSRLEQAYCGTI 206

  Fly   237 GVEYMQITSLTKTNWLRDRFEKPGGLDLTKEEKKLILERLTRSTGFENFLAKKFSSEKRFGLEGC 301
            |.|||.|....|.|||||:.|.|.......|.:.:|.:|||.||.||||||.|:::.|||||||.
plant   207 GYEYMHIADRDKCNWLRDKIETPTPRQYNSERRMVIYDRLTWSTQFENFLATKWTTAKRFGLEGA 271

  Fly   302 DIMIPAIKEVVDRATDHGVESILIGMAHRGRLNVLANICRKPISDILSQFH-GLQATD-----SG 360
            :.:||.:||:.||:.|.|||:|:|||.||||||||.|:.|||:..|.|:|. |.:..|     :|
plant   272 ESLIPGMKEMFDRSADLGVENIVIGMPHRGRLNVLGNVVRKPLRQIFSEFSGGTRPVDEVGLYTG 336

  Fly   361 SGDVKYHLGVFQERLNRQTNRMVRITVVANPSHLEHVNPVLLGKARAEMFQRGDTCGSTVMPIII 425
            :||||||||...:|..| ..:.:.:::||||||||.|:||::||.||:.:...|...:..|.|:|
plant   337 TGDVKYHLGTSYDRPTR-GGKHLHLSLVANPSHLEAVDPVVIGKTRAKQYYTKDENRTKNMGILI 400

  Fly   426 HGDASFSGQGVVYESMHLSDLPNYTTYGTIHIVSNNQVGFTTDPRFSRSSRYCTDVAKVVNAPIL 490
            |||.||:|||||||::|||.||||.|.||:|||.||||.||||||..|||:|||||||.::|||.
plant   401 HGDGSFAGQGVVYETLHLSALPNYCTGGTVHIVVNNQVAFTTDPREGRSSQYCTDVAKALSAPIF 465

  Fly   491 HVNADDPEACIQCARIAIDYRTRFKKDVVIDIVGYRRNGHNEADEPMFTQPLMYQRIKKLKPCLQ 555
            ||||||.||.:....:|.::|..|..|||:|:|.|||.||||.|||.||||.||:.|:.....||
plant   466 HVNADDIEAVVHACELAAEWRQTFHSDVVVDLVCYRRFGHNEIDEPSFTQPKMYKVIRSHPSSLQ 530

  Fly   556 LYADKLIKEGVVTDSEFKAMVSSYEKICEDAWAKSKTIKTIKYSSWIDSPWPGFFEGRDRLKLCP 620
            :|.:||::.|.||..:...:......|..:.:..||.....| ..|:.|.|.||.......::..
plant   531 IYQEKLLQSGQVTQEDIDKIQKKVSSILNEEYEASKDYIPQK-RDWLASHWTGFKSPEQISRIRN 594

  Fly   621 TGISTDTLKTIGNMFSTPPPPEHKFETHKGILRILAQRTQMVQD-KVADWSLGEAFAFGSLLKEG 684
            ||:..:.||.:|...||.|   ..|:.|:|:.|:..||.||::. :..||.||||.||.:|:.||
plant   595 TGVKPEILKNVGKAISTFP---ENFKPHRGVKRVYEQRAQMIESGEGIDWGLGEALAFATLVVEG 656

  Fly   685 IHVRLSGQDVERGTFSHRHHVLHHQSEDKVVYNSLDHLYPDQAP--YSVSNSSLSECAVLGFEHG 747
            .||||||||||||||||||.|||.| |....|..||||..:|.|  ::||||||||..|||||.|
plant   657 NHVRLSGQDVERGTFSHRHSVLHDQ-ETGEEYCPLDHLIKNQDPEMFTVSNSSLSEFGVLGFELG 720

  Fly   748 YSMASPNALVMWEGQFGDFCNTAQCIIDTFIASGETKWVRQSGVVMLLPHSMEGMGPEHSSGRIE 812
            |||.:||:||:||.|||||.|.||.:.|.||:|||.||:||:|:|:||||..:|.||||||||:|
plant   721 YSMENPNSLVIWEAQFGDFANGAQVMFDQFISSGEAKWLRQTGLVVLLPHGYDGQGPEHSSGRLE 785

  Fly   813 RFLQMSDDDPDVYPDTCDADFVARQLMNVNWIVTNLSTPANLFHCLRRQVKMGFRKPLINFSPKS 877
            ||||||||:|.|.|:....  :.:|:...||.|.|::||||.||.||||:...||||||..:||:
plant   786 RFLQMSDDNPYVIPEMDPT--LRKQIQECNWQVVNVTTPANYFHVLRRQIHRDFRKPLIVMAPKN 848

  Fly   878 LLRHPLARSPFKDFNEC----------SCFQRIIPDKGPAGKQPDCVQKLVFCSGKVYYDLVKER 932
            ||||....|...:|::.          :.|:|:|.|:.......:.:::||.|||||||:|.:||
plant   849 LLRHKQCVSNLSEFDDVKGHPGFDKQGTRFKRLIKDQSGHSDLEEGIRRLVLCSGKVYYELDEER 913

  Fly   933 DDHEQVETVALVRVEQVRRLPTRHLFLFMITMIGRILQLCPFPYDLISQQLELYPKAELLWAQEE 997
            ...| .:.||:.|||                      ||||||||||.::|:.||.||::|.|||
plant   914 KKSE-TKDVAICRVE----------------------QLCPFPYDLIQRELKRYPNAEIVWCQEE 955

  Fly   998 HKNMGAWSYVQPRFDTALLK----NENESRCVSYHGRPPSASPATGNKVQHYNEYKALI 1052
            ..|||.:.|:..|..||:..    |.|:   :.|.||.|||:.|||....|..|...|:
plant   956 PMNMGGYQYIALRLCTAMKALQRGNFND---IKYVGRLPSAATATGFYQLHVKEQTDLV 1011

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33791	NP_001027100.1	2-oxogl_dehyd_N	49..86	CDD:292696	17/36 (47%)
		sucA	50..1057	CDD:236499	463/1033 (45%)
		TPP_E1_OGDC_like	282..544	CDD:238974	153/267 (57%)
		Transket_pyr	668..880	CDD:280874	133/213 (62%)
		OxoGdeHyase_C	887..1056	CDD:293475	63/180 (35%)
AT5G65750	NP_201376.1	sucA	65..1015	CDD:236499	464/1036 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	389	1.000	Domainoid score	I150
eggNOG	1	0.900	-	-		E1_COG0567
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	902	1.000	Inparanoid score	I54
OMA	1	1.010	-	-		QHG62893
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000624
OrthoInspector	1	1.000	-	-		mtm968
orthoMCL	1	0.900	-	-		OOG6_100311
Panther	1	1.100	-	-	O	PTHR23152
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X894
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.830