Protein Alignment CG33791 and Nc73EF

DIOPT Version :9

• Sequence 1: NP_001027100.1
• Gene: CG33791 / 317974
• FlyBaseID: FBgn0035240
• Length: 1282
• Species: Drosophila melanogaster
• Sequence 2: NP_001097629.1
• Gene: Nc73EF / 39899
• FlyBaseID: FBgn0010352
• Length: 1105
• Species: Drosophila melanogaster
• Alignment Length: 1174
• Identity: 649/1174 - (55%)
• Similarity: 792/1174 - (67%)
• Gaps: 128/1174 - (10%)

  Fly    27 VLARQALRTIQTTSQRRGVHDLDSFANGCSAAYIEGLYNKWKRNPSSVDESWNELFSSNDW-SSP 90
            |.|..|:||..:.:       .:.||||.:|:|:|.:||.|.|:|:||..||:..|.||.: |.|
  Fly    36 VTAAAAVRTYNSAA-------AEPFANGSTASYVEEMYNAWLRDPTSVHTSWDAYFRSNSYVSPP 93

  Fly    91 KRSPLQVSHSRKYRRPPVERIAVKARSGERTA-SGGASAAPAAPPSDWKNIDDHHVIQAIIRAYQ 154
            ..:|:|                  |.:...|| :.|.:.|.|||  |.|.||||..:|||||:||
  Fly    94 NLAPVQ------------------ANTLPLTAFNFGGAVAGAAP--DSKTIDDHLAVQAIIRSYQ 138

  Fly   155 SRGHLAADLDPLGIVGPKKRTSVDGTQRHAAREVLRQHFSYIFNDLNTVFKLPSSTMIGGDQEFL 219
            .|||..|.||||.|..|:    :.|   :::.:.:..:||:...|::..|||||:|.||||:..|
  Fly   139 IRGHNIAHLDPLEINTPE----LPG---NSSTKSIYANFSFGEQDMDRQFKLPSTTFIGGDEASL 196

  Fly   220 SLKEILDRLERIYCGHIGVEYMQITSLTKTNWLRDRFEKPGGLDLTKEEKKLILERLTRSTGFEN 284
            .|||||:|||.:||..||||:|.|.||.:.||:|.|||.||.|:.:.|||:|||.||||:||||.
  Fly   197 PLKEILNRLENVYCNKIGVEFMFINSLEQCNWIRKRFETPGVLNFSPEEKRLILARLTRATGFEA 261

  Fly   285 FLAKKFSSEKRFGLEGCDIMIPAIKEVVDRATDHGVESILIGMAHRGRLNVLANICRKPISDILS 349
            |||||:|||||||||||:|||||:||::|.:|:.||||:::||.||||||.|||:||||::.|.:
  Fly   262 FLAKKYSSEKRFGLEGCEIMIPALKEIIDVSTELGVESVIMGMPHRGRLNTLANVCRKPLNQIFT 326

  Fly   350 QFHGLQATDSGSGDVKYHLGVFQERLNRQTNRMVRITVVANPSHLEHVNPVLLGKARAEMFQRGD 414
            ||.||:|.|.||||||||||.:.|||||.||:.:|:.|||||||||.|:||:.||.|||.|.|||
  Fly   327 QFAGLEAADDGSGDVKYHLGTYIERLNRVTNKNIRLAVVANPSHLEAVDPVVQGKTRAEQFYRGD 391

  Fly   415 TCGSTVMPIIIHGDASFSGQGVVYESMHLSDLPNYTTYGTIHIVSNNQVGFTTDPRFSRSSRYCT 479
            ..|..||.|:|||||:|.|||||||:|||||||:|||:||||:|:|||:||||||||||||.|||
  Fly   392 QEGKKVMSILIHGDAAFCGQGVVYETMHLSDLPDYTTHGTIHVVANNQIGFTTDPRFSRSSPYCT 456

  Fly   480 DVAKVVNAPILHVNADDPEACIQCARIAIDYRTRFKKDVVIDIVGYRRNGHNEADEPMFTQPLMY 544
            |||:||||||.|||||||||.:...::|.::|..|.||.|||:||||||||||.|||||||||||
  Fly   457 DVARVVNAPIFHVNADDPEAVMHVCKVAAEWRATFHKDCVIDLVGYRRNGHNEIDEPMFTQPLMY 521

  Fly   545 QRIKKLKPCLQLYADKLIKEGVVTDSEFKAMVSSYEKICEDAWAKSKTIKTIKYSSWIDSPWPGF 609
            |:|:|.|.||.|||||||.||.||..|.|::.:.||.|||:|:|.:||...:||..|:||||.||
  Fly   522 QKIRKHKNCLDLYADKLIAEGTVTAEEVKSVAAKYENICEEAFALAKTETHVKYKDWLDSPWSGF 586

  Fly   610 FEGRDRLKLCPTGISTDTLKTIGNMFSTPPPPEHKFETHKGILRILAQRTQMVQDKVADWSLGEA 674
            |||:|.||:.|||:..:||..|||.||:|||...:|..|||:||:||.|..||.:|||||:||||
  Fly   587 FEGKDPLKVAPTGVKEETLIHIGNRFSSPPPNAAEFVIHKGLLRVLAARKAMVDEKVADWALGEA 651

  Fly   675 FAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHHQSEDKVVYNSLDHLYPDQAPYSVSNSSLSEC 739
            .||||||||||||||||||||||||||||||||||..||..||||.|:||||||||||||||||.
  Fly   652 MAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHHQLVDKATYNSLQHMYPDQAPYSVSNSSLSEY 716

  Fly   740 AVLGFEHGYSMASPNALVMWEGQFGDFCNTAQCIIDTFIASGETKWVRQSGVVMLLPHSMEGMGP 804
            |||||||||||.:|||||:||.|||||.||||.|||.||:||::|||||||:||||||.||||||
  Fly   717 AVLGFEHGYSMTNPNALVLWEAQFGDFSNTAQSIIDQFISSGQSKWVRQSGLVMLLPHGMEGMGP 781

  Fly   805 EHSSGRIERFLQMSDDDPDVYPDTCDADFVARQLMNVNWIVTNLSTPANLFHCLRRQVKMGFRKP 869
            ||||.|:|||||||.||||.:|...| :|..|||.::||||.|.|||||.:|.||||:.:.||||
  Fly   782 EHSSCRVERFLQMSSDDPDYFPPESD-EFGVRQLHDINWIVANCSTPANYYHILRRQIALPFRKP 845

  Fly   870 LINFSPKSLLRHPLARSPFKDFNECSCFQRIIPDKGPAGKQPDCVQKLVFCSGKVYYDLVKERDD 934
            ||..:||||||||.|:|||.:.:|.|.|||||||.||||:.|..|:|:|||||:|||||.|.|.:
  Fly   846 LILCTPKSLLRHPEAKSPFSEMSEGSEFQRIIPDNGPAGQNPSNVKKVVFCSGRVYYDLTKTRRE 910

  Fly   935 HEQVETVALVRVEQVRRLPTRHLFLFMITMIGRILQLCPFPYDLISQQLELYPKAELLWAQEEHK 999
            .:....:|:|||||:                      .|||:||:.:|..||..|||:|||||||
  Fly   911 KQLEGEIAIVRVEQI----------------------SPFPFDLVKEQANLYKNAELVWAQEEHK 953

  Fly  1000 NMGAWSYVQPRFDTALLKNENESRCVSYHGRPPSASPATGNKVQHYNEYKALITSIFGELTPENK 1064
            |.|:|:||||||.|||    |.||.|| .....|:|..|.....|.|
  Fly   954 NQGSWTYVQPRFLTAL----NHSRDVS-QSDEQSSSTNTTTTTDHTN------------------ 995

  Fly  1065 KRIEDRIKKQQAKAKADAQSKPSTKPPAAPPK---GGSSPPPGK---GESGGKKRSD-------- 1115
                     .::...:|::|||......|.|.   ||....|.:   |:....|..|
  Fly   996 ---------HESDTDSDSKSKPWLSRMFAAPNSSTGGDPKDPAQTLGGDFNAAKHFDLKNVRHDF 1051

  Fly  1116 -------SSPSASIAPTGPAPRKPLISLPSRPPRGGKQRSGSAPAPNLVDEDSAARNREPDASAY 1173
                   ::|.|.||.||   ||  ||...| ..|....:||          .|...||.:|...
  Fly  1052 NRPAGIAAAPGARIAKTG---RK--ISYVGR-ACGASTATGS----------KAQHIRELNALLN 1100

  Fly  1174 DGAS 1177
            |..|
  Fly  1101 DAIS 1104

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33791	NP_001027100.1	2-oxogl_dehyd_N	49..86	CDD:292696	18/36 (50%)
		sucA	50..1057	CDD:236499	612/1008 (61%)
		TPP_E1_OGDC_like	282..544	CDD:238974	187/261 (72%)
		Transket_pyr	668..880	CDD:280874	163/211 (77%)
		OxoGdeHyase_C	887..1056	CDD:293475	76/168 (45%)
Nc73EF	NP_001097629.1	2-oxogl_dehyd_N	51..86	CDD:292696	17/34 (50%)
		sucA	53..1104	CDD:236499	643/1148 (56%)
		TPP_E1_OGDC_like	259..521	CDD:238974	187/261 (72%)
		Transket_pyr	645..856	CDD:280874	163/211 (77%)
		OxoGdeHyase_C	863..1102	CDD:293475	106/308 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439830
Domainoid	1	1.000	389	1.000	Domainoid score	I150
eggNOG	1	0.900	-	-		E1_COG0567
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	902	1.000	Inparanoid score	I54
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62893
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000624
OrthoInspector	1	1.000	-	-		otm51437
orthoMCL	1	0.900	-	-		OOG6_100311
Panther	1	1.100	-	-	P	PTHR23152
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X894
	11	10.800