Protein Alignment spirit and PLAT

DIOPT Version :10

• Sequence 1: NP_572492.1
• Gene: spirit / 31797
• FlyBaseID: FBgn0030051
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_000921.1
• Gene: PLAT / 5327
• HGNCID: 9051
• Length: 562
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 75/265 - (28%)
• Similarity: 124/265 - (46%)
• Gaps: 42/265 - (15%)

  Fly   132 VVGGMPTRPREFPFMAALGWRSNFDQRIYYRCGGALIANNFVLTAAHCADLGGEPPSQVRLGGDN 196
            :.||:.......|:.||:..:........:.|||.||::.::|:||||......|.....:.|..
Human   311 IKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLTVILGRT 375

  Fly   197 LTLTEGED---ISIRRVIIHPDYSASTAYNDIALLELETAA------KPELKPTCI--------- 243
            ..:..||:   ..:.:.|:|.::...|..||||||:|::.:      ...::..|:
Human   376 YRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPD 440

  Fly   244 WTQKEVTNTLVTAIGYGQ-TSFAGLSSAQLLKVPLKSVSNEEC--QHHYQKDQLAQGVLGTQMCA 305
            ||:.|::       |||: .:.:...|.:|.:..::...:..|  ||     .|.:.|....:||
Human   441 WTECELS-------GYGKHEALSPFYSERLKEAHVRLYPSSRCTSQH-----LLNRTVTDNMLCA 493

  Fly   306 GDI------TGERDTCQGDSGGPLL-MQDGLLGYVVGITSLGQGCA-SGPPSVYTRVSSFVDWIE 362
            ||.      ....|.|||||||||: :.||.: .:|||.|.|.||. ...|.|||:|::::|||.
Human   494 GDTRSGGPQANLHDACQGDSGGPLVCLNDGRM-TLVGIISWGLGCGQKDVPGVYTKVTNYLDWIR 557

  Fly   363 GIVWP 367
            ..:.|
Human   558 DNMRP 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spirit	NP_572492.1	CLIP	51..98	CDD:197829
		Tryp_SPc	132..364	CDD:238113	74/260 (28%)
PLAT	NP_000921.1	FN1	41..83	CDD:214494
		Important for binding to annexin A2	42..52
		EGF	86..117	CDD:394967
		KR	125..209	CDD:238056
		Kringle	215..296	CDD:395005
		Tryp_SPc	313..559	CDD:238113	74/258 (29%)