Protein Alignment spirit and ACR

DIOPT Version :10

• Sequence 1: NP_572492.1
• Gene: spirit / 31797
• FlyBaseID: FBgn0030051
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_001088.2
• Gene: ACR / 49
• HGNCID: 126
• Length: 421
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 86/293 - (29%)
• Similarity: 128/293 - (43%)
• Gaps: 52/293 - (17%)

  Fly   130 VSVVGGMPTRPREFPFMAALGWRSNFDQRIYYRCGGALIANNFVLTAAHCADLGGEPPSQVRL-- 192
            |.:|||...:...:|:|.:| ....::...|:.|||:|:.:.:|||||||. :|.......||
Human    41 VRIVGGKAAQHGAWPWMVSL-QIFTYNSHRYHTCGGSLLNSRWVLTAAHCF-VGKNNVHDWRLVF 103

  Fly   193 GGDNLTLTEGEDIS-------IRRVIIHPDYSASTAYNDIALLELE-----------------TA 233
            |...:|....:.:.       :.::|||..|:::|..|||||:|:.                 .|
Human   104 GAKEITYGNNKPVKAPLQERYVEKIIIHEKYNSATEGNDIALVEITPPISCGRFIGPGCLPHFKA 168

  Fly   234 AKPELKPTCIWTQKEVTNTLVTAIGYGQTSFAGLSSAQLLKVPLKSVSNEECQHHYQKDQLAQG- 297
            ..|....:| |         |...||.:.. |...|:.|::..:..:..:.|    ...|...|
Human   169 GLPRGSQSC-W---------VAGWGYIEEK-APRPSSILMEARVDLIDLDLC----NSTQWYNGR 218

  Fly   298 VLGTQMCAGDITGERDTCQGDSGGPLLMQDGLLG--YVVGITSLGQGCASGP-PSVYTRVSSFVD 359
            |..|.:|||...|:.|||||||||||:.:|....  .||||||.|.|||... |.:||....:::
Human   219 VQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLN 283

  Fly   360 WIEGIVWP-----AQQVTNAPQPNQMTSFSPEF 387
            ||...:..     .|..|..|...:.....|.|
Human   284 WIASKIGSNALRMIQSATPPPPTTRPPPIRPPF 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spirit	NP_572492.1	CLIP	51..98	CDD:197829
		Tryp_SPc	132..364	CDD:238113	80/261 (31%)
ACR	NP_001088.2	Tryp_SPc	42..285	CDD:214473	78/259 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..316		4/18 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..383
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	397..421