DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spirit and CG4053

DIOPT Version :9

Sequence 1:	NP_001162707.1	Gene:	spirit / 31797	FlyBaseID:	FBgn0030051	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	NP_650601.2	Gene:	CG4053 / 42070	FlyBaseID:	FBgn0038482	Length:	265	Species:	Drosophila melanogaster

Alignment Length:	239	Identity:	62/239 - (25%)
Similarity:	108/239 - (45%)	Gaps:	29/239 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 VVGGMPTRPREFPFMAALG--WRSNFDQRIYYRCGGALIANNFVLTAAHCA-DLGGEPPSQVR-L 192
            :|||........|:..::.  |:::.       |.|.::...::|||.||| |...|   .:| :
  Fly    35 IVGGQEAEDGVAPYQVSIQTIWKTHI-------CSGVILNEQWILTAGHCALDFSIE---DLRII 89

  Fly   193 GGDNLTLTEGEDISIRRVIIHPDYSASTAY-NDIALLELETAAKPELKPTCIWTQKE--VTNTLV 254
            .|.|..|..|:.:.....::|..|.....| |||||:.:..:.....:...:...:|  ...:.|
  Fly    90 VGTNDRLEPGQTLFPDEALVHCLYDIPYVYNNDIALIHVNESIIFNDRTQIVELSREQPPAGSTV 154

  Fly   255 TAIGYG--QTSFAGLSSAQLLKVPLKSVSNEECQHHYQKDQLAQGVLGTQMCAGDITGERDTCQG 317
            |..|:|  ::|:..:...|.|.:.:  :::|||:..:   ....|:....:|.....|| ..|.|
  Fly   155 TLTGWGAPESSYPTVQYLQTLNLTI--IAHEECRERW---DFHDGIDIGHICTFTREGE-GACSG 213

  Fly   318 DSGGPLLMQDGLLGYVVGITSLGQGCASGPPSVYTRVSSFVDWI 361
            ||||||:.:    |.:||:.:.|:.|..|.|.:|.....:.|||
  Fly   214 DSGGPLMWE----GKLVGLVNWGRACGVGMPDMYANTVYYQDWI 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spirit	NP_001162707.1	CLIP	51..98	CDD:197829
		Tryp_SPc	132..364	CDD:238113	62/239 (26%)
		Tryp_SPc	132..361	CDD:214473	60/237 (25%)
CG4053	NP_650601.2	Tryp_SPc	34..253	CDD:214473	60/237 (25%)
CG4053	NP_650601.2	Tryp_SPc	35..256	CDD:238113	62/239 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010