DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spirit and CG9649

DIOPT Version :9

Sequence 1:	NP_001162707.1	Gene:	spirit / 31797	FlyBaseID:	FBgn0030051	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	NP_650343.1	Gene:	CG9649 / 41727	FlyBaseID:	FBgn0038211	Length:	504	Species:	Drosophila melanogaster

Alignment Length:	400	Identity:	102/400 - (25%)
Similarity:	174/400 - (43%)	Gaps:	72/400 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 TRVYL-HLLLVSLPLLAV-------HATPAISPQSLRGIIFPVETFDECQLEDVARTKGTCR--- 64
            ||:.| ..|..|:||.|:       |..|. :||:...:.     .:|.:.|.|.|.:...|
  Fly   132 TRLSLSRTLRTSVPLAAIPPSQRTDHQWPQ-APQTNYTVY-----EEEEEEEPVQRRRPQQRPSR 190

  Fly    65 -RMEDCPS--ALNGWLERRESPKTCYFVRFDHYVCCAPAVAPIVTRSS-----QQACNELNKV-S 120
             |.:..||  .|....:..:.|        :......|:|.|..|.:.     .|...:|:.: .
  Fly   191 PRPQQAPSRPRLQPVPQLPQEP--------EFQTSARPSVHPSNTPAQASKFYPQTIGQLSGICG 247

  Fly   121 KVKEIDEFFVSVVGGMPTRPREFPFMAALGWRSNFDQ--RIY-YRCGGALIANNFVLTAAHCADL 182
            :.|.|...|:.  .|:.....:.|:||||     |:.  |.| :.|||.||:...|::||||...
  Fly   248 REKVIQTPFIH--NGIEVERGQLPWMAAL-----FEHVGRDYNFLCGGTLISARTVISAAHCFRF 305

  Fly   183 GGEP-PSQ---VRLGGDNLTL-TEGEDISIRRVIIHPDYSASTAYN-DIALLELETAAK--PELK 239
            |... |.:   |.||.::|.| :.|..:.:.|::||..|:.:...: |:|||:|.....  ..:|
  Fly   306 GSRNLPGERTIVSLGRNSLDLFSSGATLGVARLLIHEQYNPNVYTDADLALLQLSNHVDIGDYIK 370

  Fly   240 PTCIWTQKEVTNTLVT--------AIGYGQTSFAGLSSAQLLKVPLKSVSNE-ECQHHYQKDQLA 295
            |.|:|.:    |.|:.        ..|:|:.. .|..:.:|.|:....:..: ||:.:..::. |
  Fly   371 PICLWNE----NFLLELPSGHKSYVAGWGEDE-KGNRNTRLAKMTDTDIITQWECRGNLSEEN-A 429

  Fly   296 QGVLGTQMCAGDITGERDTCQGDSGGPLLMQDGLLGYVVGITSLGQ----GCASGPPSVYTRVSS 356
            :.:....:||.:.... ..|.|||||.|::|:..:..:.|:.|.||    .|....|.:||.|:.
  Fly   430 KFITSHTICASNAQAS-GPCSGDSGGGLMLQEQDIWMLRGVVSAGQRMTNRCNLTLPVIYTDVAK 493

  Fly   357 FVDWIEGIVW 366
            .::|:...:|
  Fly   494 HIEWLLSSMW 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spirit	NP_001162707.1	CLIP	51..98	CDD:197829	9/52 (17%)
		Tryp_SPc	132..364	CDD:238113	70/255 (27%)
		Tryp_SPc	132..361	CDD:214473	69/252 (27%)
CG9649	NP_650343.1	GD_N	29..124	CDD:292649
		Tryp_SPc	257..498	CDD:238113	69/254 (27%)
		Tryp_SPc	259..497	CDD:214473	69/249 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437075
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940