DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spirit and CG3088

DIOPT Version :9

Sequence 1:	NP_001162707.1	Gene:	spirit / 31797	FlyBaseID:	FBgn0030051	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	NP_648334.1	Gene:	CG3088 / 39115	FlyBaseID:	FBgn0036015	Length:	252	Species:	Drosophila melanogaster

Alignment Length:	256	Identity:	71/256 - (27%)
Similarity:	113/256 - (44%)	Gaps:	53/256 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 VVGGMPTRPREFPFMAALGW-RSNFDQRIYYRCGGALIANNFVLTAAHCADLGGEPPSQVRLGGD 195
            :..|.|....:.|::..:.: :||.      .|.|.:|.:.::||:|.|  |.|.....:..|..
  Fly    29 ITNGSPAYEGQAPYVVGMAFGQSNI------WCSGTIIGDTWILTSAQC--LTGSSGVTIYFGAT 85

  Fly   196 NL-----TLTEG--------EDISIRRVIIHPDYSASTAYNDIALLELETAAKPELKPTCIWTQK 247
            .|     |:|.|        :.:::.||   |....|...|.:||..|...:            :
  Fly    86 RLSQAQFTVTVGTSEYVTGNQHLALVRV---PRVGFSNRVNRVALPSLRNRS------------Q 135

  Fly   248 EVTNTLVTAIGYGQTSFA-GLSSAQLLKVPLKSVSNEECQHHYQKDQLAQGVLGTQMCAGDITGE 311
            ...|......|:|.|:|: ||:.| |..|.|:.:||.||...|....::..:|.|:..:|
  Fly   136 RYENWWANVCGWGVTTFSNGLTDA-LQCVDLQIMSNNECIAFYGSTTVSDQILCTRTPSG----- 194

  Fly   312 RDTCQGDSGGPLL-MQDGLLGYVVGITSL--GQGCASGPPSVYTRVSSFVDWIE---GIVW 366
            |.||.||:|.||: .||..   ||||::.  ..||..|.|:.:.|::|.:|||.   ||.:
  Fly   195 RSTCFGDAGSPLITKQDST---VVGISAFVASNGCTLGLPAGFARITSALDWIHQRTGIAY 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spirit	NP_001162707.1	CLIP	51..98	CDD:197829
		Tryp_SPc	132..364	CDD:238113	69/252 (27%)
		Tryp_SPc	132..361	CDD:214473	67/246 (27%)
CG3088	NP_648334.1	Tryp_SPc	29..246	CDD:238113	69/248 (28%)
CG3088	NP_648334.1	Tryp_SPc	29..244	CDD:214473	67/246 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437015
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940