DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spirit and CG10469

DIOPT Version :9

Sequence 1:	NP_001162707.1	Gene:	spirit / 31797	FlyBaseID:	FBgn0030051	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	NP_648025.1	Gene:	CG10469 / 38696	FlyBaseID:	FBgn0035678	Length:	267	Species:	Drosophila melanogaster

Alignment Length:	266	Identity:	72/266 - (27%)
Similarity:	117/266 - (43%)	Gaps:	64/266 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 VVGGMPTRPREFPFMAALGWRSNFDQRIYYR--------CGGALIANNFVLTAAHCADLGGEPPS 188
            ::.|...:.::.|:...|        ..|:.        |||.:::|.:::|||||..   :|.|
  Fly    24 IMNGTAAKAKQLPYQVGL--------LCYFEGSKDEPNMCGGTILSNRWIITAAHCLQ---DPKS 77

  Fly   189 ---QVRLGGDNLTLTEGEDISIRR--VIIHPDYSASTAYNDIALLEL----------ETAAKPEL 238
               :|.:....:...:.::|.:.|  .|:|..:...|..|||||::|          :.|..|..
  Fly    78 NLWKVLIHVGKVKSFDDKEIVVNRSYTIVHKKFDRKTVTNDIALIKLPKKLTFNKYIQPAKLPSA 142

  Fly   239 KPTCIWTQKEVTNTLVTAIGYGQTSFAGLSSA-QLLKVPLKSVSNEECQHHYQKDQLAQGVLGTQ 302
            |       |..|.......|:|.|:....|.. |.::.|:  :||:||:..:.|.      ||.:
  Fly   143 K-------KTYTGRKAIISGWGLTTKQLPSQVLQYIRAPI--ISNKECERQWNKQ------LGGK 192

  Fly   303 ---------MCAGDITGERDTCQGDSGGPLLMQDGLLGYVVGITSLG-QG-CASGPPSVYTRVSS 356
                     :|.....|.  .|:||||||:::.|| ...:|||.|.| .| |....|.|.|||||
  Fly   193 SKKVVHNGFICIDSKKGL--PCRGDSGGPMVLDDG-SRTLVGIVSHGFDGECKLKLPDVSTRVSS 254

  Fly   357 FVDWIE 362
            ::.||:
  Fly   255 YLKWIK 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spirit	NP_001162707.1	CLIP	51..98	CDD:197829
		Tryp_SPc	132..364	CDD:238113	72/266 (27%)
		Tryp_SPc	132..361	CDD:214473	70/263 (27%)
CG10469	NP_648025.1	Tryp_SPc	23..259	CDD:214473	70/263 (27%)
CG10469	NP_648025.1	Tryp_SPc	24..260	CDD:238113	71/264 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437059
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940